Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 22848
Gene Symbol: AAK1
AAK1 		0.010 Biomarker disease BEFREE We present here the first genome sequence of A. aquariorum strain AAk1, which was isolated as the sole pathogen from the blood of a patient with septicemia and necrotizing fasciitis. 22815437 2012
Entrez Id: 3120
Gene Symbol: HLA-DQB2
HLA-DQB2 		0.010 GeneticVariation disease BEFREE Both patients shared the HLA DQB1*0301 allele, which has been associated with susceptibility to GAS necrotizing fasciitis. 19828348 2010
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1 		0.010 GeneticVariation disease BEFREE Both patients shared the HLA DQB1*0301 allele, which has been associated with susceptibility to GAS necrotizing fasciitis. 19828348 2010
Entrez Id: 2775
Gene Symbol: GNAO1
GNAO1 		0.010 GeneticVariation disease BEFREE Both patients shared the HLA DQB1*0301 allele, which has been associated with susceptibility to GAS necrotizing fasciitis. 19828348 2010
Entrez Id: 3576
Gene Symbol: CXCL8
CXCL8 		0.010 AlteredExpression disease BEFREE The Group A Streptococcus (GAS) protease SpyCEP (also called ScpC) cleaves IL-8, and SpyCEP expression is strongly upregulated in vivo in the M1T1 GAS strains associated with life-threatening systemic disease including necrotizing fasciitis. 18692776 2008
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6 		0.010 Biomarker disease BEFREE Monomicrobial MRSA NF accounted for three cases, with all of the patients reporting a distinct "spider bite" lesion 2-3 days prior to admission. 18399783 2008
Entrez Id: 8434
Gene Symbol: RECK
RECK 		0.010 GeneticVariation disease BEFREE Necrotizing fasciitis was often associated with ST-15/emm-3. 18417661 2008
Entrez Id: 5866
Gene Symbol: RAB3IL1
RAB3IL1 		0.010 AlteredExpression disease BEFREE Antibody levels against the cell wall-attached GAS antigens SclA, SclB, and GRAB were significantly lower in patients with severe invasive disease (streptococcal toxic shock syndrome [STSS] and/or necrotizing fasciitis [NF]; n=35), compared with levels in patients with nonsevere GAS bacteremia (n=35). 14976595 2004