Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.050 GeneticVariation disease BEFREE Medullary thyroid carcinoma (MTC), a neuroendocrine tumor originating from thyroid parafollicular cells, has been demonstrated to be associated with mutations in RET, HRAS, KRAS and NRAS. 26718898 2016
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.050 GeneticVariation disease BEFREE Recent results from exome sequencing indicate that, besides mutations in RET, HRAS, and KRAS, no other recurrent driver mutations are present in MTC. 26285815 2015
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.050 GeneticVariation disease BEFREE Of the seven RET wild-type MTCs, four cases (57.1 %) harbored a RAS mutation: three in HRAS (all Q61R) and one in KRAS (G12R). 24828033 2014
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.050 GeneticVariation disease BEFREE Approximately 90% of MTCs had mutually exclusive mutations in RET, HRAS, and KRAS, suggesting that RET and RAS are the predominant driver pathways in MTC. 23264394 2013
Entrez Id: 3265
Gene Symbol: HRAS
HRAS
0.050 Biomarker disease BEFREE These studies with cultured human MTC cells provide a model system to study the role of Ha-ras and related genes in neuroendocrine differentiation. 3112776 1987