Moreover, miR-141-3p knockdown effectively reversed the effects of AIF on cell growth, migration, invasion, and EMT, while promoted PTC cell apoptosis escape.
In summary, the findings suggested that miR-141-3p can act as a tumor suppressor in PTC and may be a potential therapeutic target for PTC treatment.Anat Rec, 302:258-268, 2019.
Our results demonstrated that <i>XIST</i> functioned as an oncogene in PTC progression by regulating miR-141, suggesting that <i>XIST</i> might be a promising therapeutic target for PTC treatment.