In silico analysis showed that <i>FAM95B1</i> and <i>UCA1</i> were significantly correlated with cervical lymph node metastasis, tumor staging, and PTC prognosis (<i>P</i><0.05). qRT-PCR analysis revealed high UCA1 expression in PTC tissues and correlations between UCA1 expression levels and cervical lymph node metastasis and tumor staging in PTC, that is, higher <i>UCA1</i> expression resulted in poorer PTC prognosis.