Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 AlteredExpression disease BEFREE In addition, the number of fenestrae in the hepatic sinusoid showed notable differences between the groups, and the serum levels of MMP-8, VEGF and angiopoietin-2 were increased in the mice with liver fibrosis and reduced by carvedilol treatment. 31534314 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 AlteredExpression disease BEFREE These data suggest that RPS may treat HF primarily through downregulation of the expression levels of the mRNA and phosphorylated VEGF, ERK1/2, PDGF and α‑SMA proteins. 30864692 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 AlteredExpression disease BEFREE In vivo, the combination therapy reduced liver fibrosis (associated with increased matrix metalloproteinases expression), increased hepatocyte proliferation (associated with increased hepatocyte growth factor, vascular endothelial growth factor, and oncostatin M in the liver), and reduced blood levels of liver enzymes, more effectively than MSCs or id-BMMs monotherapy. 30394698 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 Biomarker disease BEFREE We have recently shown that targeting Vascular Endothelial Growth Factor (VEGF) specifically in scar-infiltrating myeloid cells prevented remodeling of the sinusoidal vasculature and abrogated the resolution of murine liver fibrosis, thereby unmasking an unanticipated link between angiogenesis and resolution of fibrosis. 28118605 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 GeneticVariation disease BEFREE Placental growth factor (PlGF), a member of the vascular endothelial growth factor (VEGF) family, mediates wound healing and inflammatory responses, exerting an effect on liver fibrosis and angiogenesis; however, the precise mechanism remains unclear. 28744285 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 Biomarker disease BEFREE These results suggest that levistilide A can inhibit liver fibrosis through antiangiogenesis by alleviating sinusoid capillarization via the vascular endothelial growth factor signaling pathway. 28440736 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 Biomarker disease BEFREE Our data suggest that VEGFA protein is a promising noninvasively diagnostic biomarker for HCV-induced liver fibrosis. 28472595 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 AlteredExpression disease BEFREE Endostatin/collagen XVIII expression in nontumor tissues correlated with tumor stages (P=0.014) and expression of vascular endothelial growth factor (P=0.007), but not the stages of hepatic fibrosis (P>0.05). 15605080 2005
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 Biomarker disease BEFREE Angiotensin-I-converting enzyme inhibitors may be an alternative anti-angiogenic strategy in the treatment of liver fibrosis and hepatocellular carcinoma. Possible role of vascular endothelial growth factor. 12677092 2003
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.390 Biomarker disease CTD_human Hypoxia-induced VEGF and collagen I expressions are associated with angiogenesis and fibrogenesis in experimental cirrhosis. 11981751 2002