We recently reported that chemokine C-C receptor 7 (CCR7)<sup>-</sup> /programmed cell death-1 (PD-1)<sup>+</sup> follicular helper T (Tfh) cells could be involved in AIH pathogenesis.
These results significantly extend our understanding of Tfh subsets in AIH and suggest a potential role of dysregulated chemokine C-C receptor 7<sup>-</sup> programmed cell death-1<sup>+</sup> Tfh subset in the pathogenesis and disease progression of AIH.