Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 GeneticVariation disease BEFREE Analysis of single nucleotide polymorphisms (SNPs) in the TLR4 gene did not show a significant association between D299G or T399I and AMD, nor did haplotypes containing these variants. 18172114 2008
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 Biomarker disease BEFREE TLR4 inhibitor attenuates amyloid-β-induced angiogenic and inflammatory factors in ARPE-19 cells: Implications for age-related macular degeneration. 26936827 2016
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 GeneticVariation disease BEFREE Even with previously verified samples sets and adequate study powers, the results did not confirm the reported associations of TLR3 rs3775291 and TLR4 rs4986790 with AMD in the three independent samples, individually or combined. 19628747 2009
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 GeneticVariation disease BEFREE Although an intronic SNP in TLR4 was associated marginally with AMD (P = 0.03), it was not possible to replicate a previous association with the rare coding SNP D299G in this gene (P = 0.6). 18385087 2008
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 GeneticVariation disease BEFREE Analysis of CFH, TLR4, and APOE polymorphism in India suggests the Tyr402His variant of CFH to be a global marker for age-related macular degeneration. 16936080 2006
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 GeneticVariation disease BEFREE Interestingly, the effect of TLR4, APOE and ABCA1 variants on AMD susceptibility was opposite to that of association with atherosclerosis risk. 15829498 2005
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 GeneticVariation disease BEFREE No significant association has been discovered between TLR4 rs1927907 polymorphism and AMD susceptibility. 31083239 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 Biomarker disease CTD_human Interestingly, the effect of TLR4, APOE and ABCA1 variants on AMD susceptibility was opposite to that of association with atherosclerosis risk. 15829498 2005
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.370 Biomarker disease LHGDN Analysis of single nucleotide polymorphisms (SNPs) in the TLR4 gene did not show a significant association between D299G or T399I and AMD, nor did haplotypes containing these variants. 18172114 2008