Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group RGD Phenotypic characterization of recessive gene knockout rat models of Parkinson's disease. 24969022 2014
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Familial Parkinsonism with digenic parkin and PINK1 mutations. 18546294 2008
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE PINK1 and Parkin, the products of two genes responsible for autosomal recessive Parkinsonian syndromes with early onset, act as a quality control system on the outer mitochondrial membrane to preserve mitochondrial integrity. 23206589 2013
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group CTD_human This region contains a novel locus for autosomal recessive early-onset parkinsonism, PARK6. 11254447 2001
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group LHGDN We genotyped eight known mutations in three clinic-based cohorts with Parkinsonism and found one homozygous p.L347P mutation in PINK1. 17055324 2007
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Two new AREP loci (PARK6 and PARK7) have been recently mapped on chromosome 1p and confirmed in independent datasets, suggesting that both might be frequent. 12548343 2002
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE Our data indicate that olfactory dysfunction is common in PINK1 Parkinsonism and consists typically in defective odor identification and discrimination. 19890973 2009
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE PINK1 mutation in Taiwanese early-onset parkinsonism : clinical, genetic, and dopamine transporter studies. 17960343 2007
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group HPO
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism. 15970950 2005
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE The aim of this study was to elucidate whether sensory abnormalities are present and may precede motor symptoms in familial parkinsonism by characterizing sensory function in symptomatic and asymptomatic PINK1 mutation carriers. 19372294 2009
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE Mutations associated with early-onset autosomal recessive parkinsonism have been identified in the Parkin gene, and recently a second gene, PARK6, involved in early-onset recessive parkinsonism was localized on chromosome 1p35-36. 11462174 2001
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group LHGDN [Case of a 30-year history of PARK6 --findings from functional imaging of the brain]. 19048950 2008
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Phenotypic spectrum of PINK1-associated parkinsonism in 15 mutation carriers from 1 family. 17013904 2007
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Neuropsychiatric and cognitive features in autosomal-recessive early parkinsonism due to PINK1 mutations. 17260336 2007
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE A Novel Homozygous p.L539F Mutation Identified in PINK1 Gene in a Moroccan Patient with Parkinsonism. 27413743 2016
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE Recent evidence from studies on the genetic forms of parkinsonism with particular stress on DJ-1, parkin, and PINK-1 also suggest the involvement of mitochondria and oxidative stress. 23064436 2013
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 CausalMutation group CLINVAR
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE Mutations in seven genes are robustly associated with autosomal dominant (SNCA, LRRK2, EIF4G1, VPS35) or recessive (parkin/PARK2, PINK1, DJ1/PARK7) Parkinson's disease (PD) or parkinsonism. 23462481 2013
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE The results indicate worldwide distribution of PARK6-linked parkinsonism. 15505170 2004
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Familial Parkinsonism is associated with loss-of-function mutations in PINK1 and Parkin. 27593930 2017
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation. 18473170 2008
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group CTD_human Methylmercury can induce Parkinson's-like neurotoxicity similar to 1-methyl-4- phenylpyridinium: a genomic and proteomic analysis on MN9D dopaminergic neuron cells. 26558463 2015
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Mutations in PTEN-induced kinase 1 (PINK1) are associated with familial parkinsonism and neuropsychiatric disorders. 19279012 2009
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE To date, no pathology or functional imaging studies are available on PARK6-linked parkinsonism. 12447943 2002