Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group HPO
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 CausalMutation group CLINVAR
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Parkinsonism due to mutations in PINK1, parkin, and DJ-1 and oxidative stress and mitochondrial pathways. 22951446 2012
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE PARK6 is a common cause of familial parkinsonism. 12548371 2002
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group LHGDN PARK6 is a common cause of familial parkinsonism. 12548371 2002
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE PINK1, Parkin, and DJ-1 mutations in Italian patients with early-onset parkinsonism. 15970950 2005
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE PINK1 homozygous W437X mutation in a patient with apparent dominant transmission of parkinsonism. 16700027 2006
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE PINK1 mutation in Taiwanese early-onset parkinsonism : clinical, genetic, and dopamine transporter studies. 17960343 2007
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE PINK1-linked parkinsonism is associated with Lewy body pathology. 20356854 2010
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE PINK1 parkinsonism and Parkinson disease: distinguishable brain mitochondrial function and metabolomics. 23063710 2013
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE PINK1 and Parkin, the products of two genes responsible for autosomal recessive Parkinsonian syndromes with early onset, act as a quality control system on the outer mitochondrial membrane to preserve mitochondrial integrity. 23206589 2013
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE PINK1 (PTEN induced putative kinase 1) and PARKIN (also known as PARK2) have been identified as the causal genes responsible for hereditary recessive early-onset Parkinsonism. 24784582 2014
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE PINK1-type of early-onset parkinsonism can occur in very young patients, and phenotypic expression of PINK1 mutations may depend on age of onset and ethnicity. 28062148 2017
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE A Novel Homozygous p.L539F Mutation Identified in PINK1 Gene in a Moroccan Patient with Parkinsonism. 27413743 2016
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group LHGDN All sites of mutations were novel, suggesting that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. 15349870 2004
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE All sites of mutations were novel, suggesting that PINK1 may be the second most common causative gene next to parkin in parkinsonism with the recessive mode of inheritance. 15349870 2004
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Analysis of the PINK1 gene in a cohort of patients with sporadic early-onset parkinsonism in Taiwan. 16257123 2006
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group BEFREE Bilateral subthalamic stimulation in Parkin and PINK1 parkinsonism. 18378882 2008
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Deficits in temporal processing might be considered as subclinical signs of alteration at least in PINK1-related parkinsonism. 18584234 2008
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group CTD_human Downregulation of Pink1 influences mitochondrial fusion-fission machinery and sensitizes to neurotoxins in dopaminergic cells. 24792327 2014
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes. 16009891 2005
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group LHGDN Early-onset parkinsonism associated with PINK1 mutations: frequency, genotypes, and phenotypes. 16009891 2005
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 Biomarker group CTD_human Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease. 24441527 2014
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Familial Parkinsonism with digenic parkin and PINK1 mutations. 18546294 2008
Entrez Id: 65018
Gene Symbol: PINK1
PINK1
0.700 GeneticVariation group BEFREE Familial Parkinsonism is associated with loss-of-function mutations in PINK1 and Parkin. 27593930 2017