Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.080 GeneticVariation phenotype BEFREE For JAK2 V617F, the most frequent mutation in myeloproliferative neoplasms, accurate determination of mutational loads is of interest at diagnosis, for phenotypic and prognostic purposes, and during follow-up for minimal residual disease assessment. 26596525 2016
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.080 GeneticVariation phenotype BEFREE Establishing optimal quantitative-polymerase chain reaction assays for routine diagnosis and tracking of minimal residual disease in JAK2-V617F-associated myeloproliferative neoplasms: a joint European LeukemiaNet/MPN&MPNr-EuroNet (COST action BM0902) study. 23860450 2013
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.080 GeneticVariation phenotype BEFREE QuanTAS-PCR is a simple, cost-efficient, closed-tube method for JAK2 V617F mutation quantification that can detect very low levels of the mutant allele, thus enabling analysis of minimal residual disease. 23617802 2013
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.080 GeneticVariation phenotype BEFREE Monitoring of minimal residual disease in patients with core binding factor acute myeloid leukemia and the impact of C-KIT, FLT3, and JAK2 mutations on clinical outcome. 19603346 2009
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.080 GeneticVariation phenotype BEFREE The combination of ARMS-PCR and capillary electrophoresis enables quantitative assay of JAK2 V617F mutation, which helps in chronic MPD diagnosis and estimation of minimal residual disease. 19215672 2009
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.080 GeneticVariation phenotype BEFREE In conclusion, allogeneic stem cell transplantation after dose-reduced conditioning induces high rates of molecular remission in JAK2-positive patients with myelofibrosis, and quantification of V617F-JAK2 mutation by real-time PCR allows the detection of minimal residual disease to guide adoptive immunotherapy. 17018857 2007
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.080 GeneticVariation phenotype BEFREE Although an amplification refractory mutation system (ARMS) was shown to be slightly superior in terms of sensitivity, our real-time PCR method provides the potential for quantification of the JAK2 V617F mutation, having potential future applications in the monitoring of minimal residual disease or predicting outcome of disease severity. 17251334 2007
Entrez Id: 3717
Gene Symbol: JAK2
JAK2
0.080 GeneticVariation phenotype BEFREE Our presented data shows the feasibility of the detection of JAK2 gene mutation by real-time PCR as a minimal residual disease marker after transplant. 17565328 2007