Gene: F5 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 Biomarker disease BEFREE Lack of association between factor V Leiden and sepsis: a meta-analysis. 23804230 2015
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 GeneticVariation disease BEFREE Survival advantage of heterozygous factor V Leiden carriers in murine sepsis. 25690763 2015
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 Biomarker disease BEFREE Hypothetically, patients with factor V Leiden may suffer from more severe coagulopathy in case of severe infection or sepsis. 22961823 2012
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 Biomarker disease BEFREE Hypothetically, patients with factor V Leiden may suffer from more severe coagulopathy in cases of severe infection or sepsis. 22198860 2011
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 GeneticVariation disease BEFREE The high prevalence of the prothrombotic factor V Leiden (FVL) mutation in whites has been attributed to a positive selection pressure (eg, resulting from reduced blood loss or improved survival in sepsis). 21389321 2011
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 GeneticVariation disease BEFREE In this study, the relationship between the TNF-alpha 308G/A, the IL-6-174 G/C, the PAI-1, the FVL, the EPCR, and the Cathepsin G (Ars 125 Ser) polymorphisms and the development and outcome of sepsis in pediatric patients was studied. 16444434 2006
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 GeneticVariation disease LHGDN Influence of the factor V Leiden mutation on infectious disease susceptibility and outcome: a population-based study. 16235188 2005
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 GeneticVariation disease LHGDN Survival advantage associated with heterozygous factor V Leiden mutation in patients with severe sepsis and in mouse endotoxemia. 12869495 2003
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 GeneticVariation disease BEFREE Three of these six children with FVL mutation had ventriculoatrial shunt for hydrocephalus, two children had cardiomyopathy and one had sepsis. 11952004 2002
Entrez Id: 2153
Gene Symbol: F5
F5 		0.290 Therapeutic disease RGD Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis. 12000738 2002