Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 94103
Gene Symbol: ORMDL3
ORMDL3 		0.200 GeneticVariation disease BEFREE 17q21 locus and ORMDL3: an increased risk for childhood asthma. 24165737 2014
Entrez Id: 94103
Gene Symbol: ORMDL3
ORMDL3 		0.200 Biomarker disease BEFREE Childhood asthma and atopy are associated with chromosome 17q21 in Chinese, but such association may involve genes other than ORMDL3 in this region. 19175592 2009
Entrez Id: 120227
Gene Symbol: CYP2R1
CYP2R1 		0.010 GeneticVariation disease BEFREE Childhood asthma and spirometric indices are associated with polymorphic markers of two vitamin D 25-hydroxylase genes. 25845986 2015
Entrez Id: 55876
Gene Symbol: GSDMB
GSDMB 		0.170 GeneticVariation disease BEFREE Childhood asthma was associated with GSDMB_rs2305480 (odds ratio [OR] 0.69, 95% confidence interval [CI] 0.57-0.83). 26534891 2016
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.040 Biomarker disease BEFREE Toll-like receptor 2 as a major gene for asthma in children of European farmers. 15007351 2004
Entrez Id: 80332
Gene Symbol: ADAM33
ADAM33 		0.100 GeneticVariation disease BEFREE ADAM33 polymorphisms and phenotype associations in childhood asthma. 15208587 2004
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.040 GeneticVariation disease BEFREE Glutathione S-transferase P1 gene polymorphism and air pollution as interactive risk factors for childhood asthma. 15544594 2004
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.030 Biomarker disease BEFREE Intercellular adhesion molecule-1 and childhood asthma. 16021473 2005
Entrez Id: 154
Gene Symbol: ADRB2
ADRB2 		0.070 GeneticVariation disease BEFREE ADRB2 polymorphisms might predict a small component of the long-term prognosis in childhood asthma, but are not important determinants of asthma incidence or prevalence in the British population. 16935688 2006
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		0.010 GeneticVariation disease BEFREE EPHX1 and GSTP1 variants contribute to the occurrence of childhood asthma and increase asthma susceptibility to exposures from major roads. 17711870 2007
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.040 GeneticVariation disease BEFREE Glutathione S-transferase P1, maternal smoking, and asthma in children: a haplotype-based analysis. 18335111 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA 		0.010 GeneticVariation disease BEFREE VEGF polymorphisms are associated with childhood asthma, lung function and airway responsiveness in two populations, suggesting that VEGF polymorphisms influence asthma susceptibility, airflow obstruction and airways responsiveness. 19196819 2009
Entrez Id: 383
Gene Symbol: ARG1
ARG1 		0.030 GeneticVariation disease BEFREE ARG1 and ARG2 loci are associated with childhood asthma. 19281908 2009
Entrez Id: 30009
Gene Symbol: TBX21
TBX21 		0.120 GeneticVariation disease BEFREE TBX21 gene variants increase childhood asthma risk in combination with HLX1 variants. 19362357 2009
Entrez Id: 9670
Gene Symbol: IPO13
IPO13 		0.010 GeneticVariation disease BEFREE Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma. 19619331 2009
Entrez Id: 3565
Gene Symbol: IL4
IL4 		0.100 GeneticVariation disease BEFREE IL4-RA Q551R and TGF-beta1 C-509T are single nucleotide polymorphism loci with significant association to childhood asthma, but they do not have synergistic effects. 19657898 2009
Entrez Id: 4321
Gene Symbol: MMP12
MMP12 		0.010 Biomarker disease BEFREE Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults. 20546881 2010
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.040 Biomarker disease BEFREE Glutathione S-transferase, incense burning and asthma in children. 21109554 2011
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.100 GeneticVariation disease BEFREE Tumour necrosis factor G-308A polymorphism modifies the effect of home dampness on childhood asthma. 21307151 2011
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.030 GeneticVariation disease BEFREE IFNG genotype and sex interact to influence the risk of childhood asthma. 21798578 2011
Entrez Id: 133482
Gene Symbol: SLCO6A1
SLCO6A1 		0.020 GeneticVariation disease BEFREE GST genes polymorphisms may play an important role in pathogenesis and susceptibility to asthma in children. 22326267 2012
Entrez Id: 373156
Gene Symbol: GSTK1
GSTK1 		0.020 GeneticVariation disease BEFREE GST genes polymorphisms may play an important role in pathogenesis and susceptibility to asthma in children. 22326267 2012
Entrez Id: 5097
Gene Symbol: PCDH1
PCDH1 		0.020 GeneticVariation disease BEFREE Protocadherin-1 polymorphisms may specifically affect the development of non-atopic asthma in children. 23050600 2012
Entrez Id: 929
Gene Symbol: CD14
CD14 		0.060 PosttranslationalModification disease BEFREE CD14 methylation levels were quantified in 157 children from the prospective Environment and Childhood Asthma birth cohort at ages 2 and 10. 23194293 2012
Entrez Id: 3596
Gene Symbol: IL13
IL13 		0.200 GeneticVariation disease BEFREE IL-13 A2044G and RANTES G-28C are significantly associated with childhood asthma. 24053708 2013