Gene: MBD4 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 8930
Gene Symbol: MBD4
MBD4 		0.030 Biomarker disease BEFREE Although patients with advanced colorectal cancer (CRC) exhibiting a mismatch repair (MMR) deficiency reportedly do not benefit from 5-fluorouracil-based chemotherapy and we previously reported that truncated methyl-CpG binding domain protein 4 (MBD4) enhances 5-fluorouracil cytotoxicity in MMR-deficient CRC cells, little is known regarding the effect of MMR deficiency on trifluridine cytotoxicity in CRC. 29545913 2018
Entrez Id: 8930
Gene Symbol: MBD4
MBD4 		0.030 GeneticVariation disease BEFREE Therefore, it has been postulated that mutations in MBD4 may result in mismatch repair deficiency. 12935920 2003
Entrez Id: 8930
Gene Symbol: MBD4
MBD4 		0.030 GeneticVariation disease BEFREE Somatic frameshift mutations in the MBD4 gene of sporadic colon cancers with mismatch repair deficiency. 10637515 1999