Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.300 Biomarker disease CTD_human Genetic variation associated with the occurrence and progression of neurological disorders. 27713094 2017
Entrez Id: 57216
Gene Symbol: VANGL2
VANGL2 		0.300 Biomarker disease CTD_human A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene. 21404367 2011
Entrez Id: 5444
Gene Symbol: PON1
PON1 		0.300 Biomarker disease CTD_human Paraoxonase 1 polymorphisms and haplotypes and the risk for having offspring affected with spina bifida in Southeast Mexico. 21031563 2010
Entrez Id: 25828
Gene Symbol: TXN2
TXN2 		0.300 Biomarker disease CTD_human Genetic polymorphisms in the thioredoxin 2 (TXN2) gene and risk for spina bifida. 19165900 2009
Entrez Id: 1072
Gene Symbol: CFL1
CFL1 		0.300 Biomarker disease CTD_human Association between CFL1 gene polymorphisms and spina bifida risk in a California population. 17352815 2007
Entrez Id: 5077
Gene Symbol: PAX3
PAX3 		0.300 Biomarker disease CTD_human Screening for novel PAX3 polymorphisms and risks of spina bifida. 17149730 2007
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.300 Biomarker disease CTD_human Maternal genotype for the monocyte chemoattractant protein 1 A(-2518)G promoter polymorphism is associated with the risk of spina bifida in offspring. 16596675 2006
Entrez Id: 5130
Gene Symbol: PCYT1A
PCYT1A 		0.300 Biomarker disease CTD_human CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. 17184542 2006
Entrez Id: 5110
Gene Symbol: PCMT1
PCMT1 		0.300 Biomarker disease CTD_human A known functional polymorphism (Ile120Val) of the human PCMT1 gene and risk of spina bifida. 16256389 2006
Entrez Id: 1119
Gene Symbol: CHKA
CHKA 		0.300 Biomarker disease CTD_human CHKA and PCYT1A gene polymorphisms, choline intake and spina bifida risk in a California population. 17184542 2006
Entrez Id: 5077
Gene Symbol: PAX3
PAX3 		0.300 Biomarker disease CTD_human Effect of arsenite, maternal age, and embryonic sex on spina bifida, exencephaly, and resorption rates in the splotch mouse. 12854658 2003
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		0.300 Biomarker disease CTD_human A human YAC transgene rescues craniofacial and neural tube development in PDGFRalpha knockout mice and uncovers a role for PDGFRalpha in prenatal lung growth. 11023856 2000
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2 		0.300 Biomarker disease CTD_human FGFR2 mutation associated with clinical manifestations consistent with Antley-Bixler syndrome. 9605588 1998
Entrez Id: 5077
Gene Symbol: PAX3
PAX3 		0.300 Biomarker disease CTD_human Experimental teratological studies with the mouse CNS mutations cranioschisis and delayed splotch. 3902948 1985
Entrez Id: 5077
Gene Symbol: PAX3
PAX3 		0.300 Biomarker disease CTD_human Gene-teratogen interaction and its morphological basis in retinoic acid-induced mouse spina bifida. 6385329 1984
Entrez Id: 7050
Gene Symbol: TGIF1
TGIF1 		0.010 GeneticVariation disease BEFREE The study focused on the associated brain malformations, including neuronal migration defects, which predominated in individuals with ZIC2 mutations, and neural tube defects, which were frequently associated with ZIC2 (rachischisis) and TGIF mutations. 21940735 2011
Entrez Id: 7546
Gene Symbol: ZIC2
ZIC2 		0.010 GeneticVariation disease BEFREE The study focused on the associated brain malformations, including neuronal migration defects, which predominated in individuals with ZIC2 mutations, and neural tube defects, which were frequently associated with ZIC2 (rachischisis) and TGIF mutations. 21940735 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10 		0.010 GeneticVariation disease BEFREE The study focused on the associated brain malformations, including neuronal migration defects, which predominated in individuals with ZIC2 mutations, and neural tube defects, which were frequently associated with ZIC2 (rachischisis) and TGIF mutations. 21940735 2011