Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10919
Gene Symbol: EHMT2
EHMT2
0.300 Therapeutic disease CTD_human We evaluated the effects of pharmacological and RNAi-mediated inhibition of EHMT2 on the transcription of IFN-β and other IFN-inducible antiviral genes, as well as its effect on foot-and-mouth disease virus (FMDV) and vesicular stomatitis virus (VSV) replication in bovine cells. 26418342 2016
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 Biomarker disease BEFREE Moreover, we infected A549 cells with vesicular stomatitis virus (VSV) and found that induction of IFN-β and IL-6 mRNA after VSV infection was decreased by BinCARD2 knockdown. 30795865 2019
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 AlteredExpression disease BEFREE One of the major mechanisms of resistance to VSV infection is the type I interferon (IFN) response, leading to the development of VSV expressing IFNβ which will lead to resistance of viral replication in normal cells which have intact IFN signaling but allow replication in cancer cells with defective IFNβ signaling. 30622322 2019
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 Biomarker disease BEFREE In the present study, we demonstrated that the PDCoV nucleocapsid (N) protein antagonizes porcine IFN-β production after vesicular stomatitis virus (VSV) infection or poly(I:C) stimulation. 31143181 2019
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 AlteredExpression disease BEFREE Two human IFNs which have been produced for clinical use, IFN-α2a and IFN-β, were compared for activity in protecting human head and neck squamous cell carcinoma (HNSCC) lines from oncolysis by vesicular stomatitis virus (VSV). 25995245 2015
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 Biomarker disease BEFREE Notably, this effect was only apparent for HSV-1, as the CK2 inhibitors did not enhance the antiviral effect of IFN-β on either vesicular stomatitis virus or adenovirus type 5. 21722672 2011
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 AlteredExpression disease BEFREE Safety studies on intrahepatic or intratumoral injection of oncolytic vesicular stomatitis virus expressing interferon-beta in rodents and nonhuman primates. 19911974 2010
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 Biomarker disease BEFREE In the eight resistant lines, pretreatment with IFN-beta prevented lysis of cells by VSV.GFP, and VSV infection or addition of IFN-beta protein resulted in the upregulation of double-stranded RNA-dependent protein kinase (PKR), myxovirus resistance A (MxA), and 2',5'-oligo-adenylate-synthetase (2'5'-OAS) mRNA. 19715403 2010
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 Biomarker disease BEFREE Based on the hypotheses that a replication-competent vesicular stomatitis virus (VSV) oncolytic vector would transduce more tumor cells in vivo, that coexpression of the immunostimulatory IFN-beta gene would enhance the immune-based effector mechanisms associated both with regression of mesotheliomas and with VSV-mediated virotherapy, and that virus-derived IFN-beta would add further safety to the VSV platform, we tested the use of IFN-beta as a therapeutic transgene expressed from VSV as a novel treatment for mesothelioma. 19773437 2009
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.090 Biomarker disease BEFREE Nonetheless, pretreatment with interferon beta (IFNbeta) virtually eliminated VSV infection in healthy tissues without impeding any oncolytic effects on tumor cells. 15200120 2004
Entrez Id: 9172
Gene Symbol: MYOM2
MYOM2
0.060 GeneticVariation disease BEFREE Immunogenicity in African Green Monkeys of M Protein Mutant Vesicular Stomatitis Virus Vectors and Contribution of Vector-Encoded Flagellin. 29562688 2018
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.060 GeneticVariation disease BEFREE For VSV-CD30 the VSV glycoprotein G reading frame was replaced by those of the CD30-targeted MV glycoproteins. 29560124 2018
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.060 Biomarker disease BEFREE Differential requirement for N-ethylmaleimide-sensitive factor in endosomal trafficking of transferrin receptor from anterograde trafficking of vesicular stomatitis virus glycoprotein G. 27995606 2017
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.060 Biomarker disease BEFREE These LV efficiently transfer genes into relevant targets and are more resistant to complement-mediated inactivation, because of reduced content of the vesicular stomatitis virus envelope glycoprotein G compared to vectors produced by transient transfection. 28835507 2017
Entrez Id: 100616444
Gene Symbol: ERVK-20
ERVK-20
0.060 Biomarker disease BEFREE These LV efficiently transfer genes into relevant targets and are more resistant to complement-mediated inactivation, because of reduced content of the vesicular stomatitis virus envelope glycoprotein G compared to vectors produced by transient transfection. 28835507 2017
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.060 Biomarker disease BEFREE While the most common example is the envelope glycoprotein from vesicular stomatitis virus (VSVG), many other viral proteins have also been used. 28870117 2017
Entrez Id: 30816
Gene Symbol: ERVW-1
ERVW-1
0.060 Biomarker disease BEFREE While the most common example is the envelope glycoprotein from vesicular stomatitis virus (VSVG), many other viral proteins have also been used. 28870117 2017
Entrez Id: 30816
Gene Symbol: ERVW-1
ERVW-1
0.060 Biomarker disease BEFREE Although the tropism of VSV is broad, and its envelope glycoprotein G is often used for pseudotyping other viruses, the host cellular components involved in VSV infection remain unclear. 28842478 2017
Entrez Id: 30816
Gene Symbol: ERVW-1
ERVW-1
0.060 Biomarker disease BEFREE These LV efficiently transfer genes into relevant targets and are more resistant to complement-mediated inactivation, because of reduced content of the vesicular stomatitis virus envelope glycoprotein G compared to vectors produced by transient transfection. 28835507 2017
Entrez Id: 100616444
Gene Symbol: ERVK-20
ERVK-20
0.060 Biomarker disease BEFREE While the most common example is the envelope glycoprotein from vesicular stomatitis virus (VSVG), many other viral proteins have also been used. 28870117 2017
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.060 Biomarker disease BEFREE Although the tropism of VSV is broad, and its envelope glycoprotein G is often used for pseudotyping other viruses, the host cellular components involved in VSV infection remain unclear. 28842478 2017
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.060 Biomarker disease BEFREE Although the tropism of VSV is broad, and its envelope glycoprotein G is often used for pseudotyping other viruses, the host cellular components involved in VSV infection remain unclear. 28842478 2017
Entrez Id: 64006
Gene Symbol: ERVK-6
ERVK-6
0.060 Biomarker disease BEFREE These LV efficiently transfer genes into relevant targets and are more resistant to complement-mediated inactivation, because of reduced content of the vesicular stomatitis virus envelope glycoprotein G compared to vectors produced by transient transfection. 28835507 2017
Entrez Id: 100616444
Gene Symbol: ERVK-20
ERVK-20
0.060 Biomarker disease BEFREE Although the tropism of VSV is broad, and its envelope glycoprotein G is often used for pseudotyping other viruses, the host cellular components involved in VSV infection remain unclear. 28842478 2017
Entrez Id: 30816
Gene Symbol: ERVW-1
ERVW-1
0.060 Biomarker disease BEFREE Usual lentiviral vectors (LVs) pseudotyped with vesicular stomatitis virus envelope glycoprotein poorly transduced healthy and malignant PCs. 22318450 2012