Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2554
Gene Symbol: GABRA1
GABRA1
0.320 Biomarker disease BEFREE Some clinical and experimental data suggest a possible role of gamma-aminobutyrate (GABA)-ergic mechanisms in the pathophysiology of essential tremor (ET), such as the improvement of ET with some GABAergic drugs and the development of an experimental model of ET in GABA A receptor alpha-1 knockout mice (postural and kinetic tremor and motor incoordination similar to human ET). 20820800 2011
Entrez Id: 2554
Gene Symbol: GABRA1
GABRA1
0.320 GeneticVariation disease BEFREE Since the 156T>C variant appears to be not pathogenically relevant, our results suggest that missense, nonsense or splice site mutation in the coding region of the GABRA1 gene is not a major genetic cause of ET in Caucasian subjects. 16530959 2006
Entrez Id: 2554
Gene Symbol: GABRA1
GABRA1
0.320 Biomarker disease CTD_human Genetic essential tremor in gamma-aminobutyric acidA receptor alpha1 subunit knockout mice. 15765150 2005