Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
0.050 Biomarker disease BEFREE Among the genetic factors for isolated AAD and autoimmune polyendocrine syndrome type 2, a key role is played by HLA class II genes: HLA-DRB1*0301-DQA1*0501-DQB1*0201 and DRB1*04-DQA1*0301-DQB1*0302 are positively, and DRB1*0403 is negatively, associated with genetic risk for AAD. 27211051 2016
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
0.050 Biomarker disease BEFREE After conditioning on DRB1, association with AAD was still present for HLA-B and MICA, suggesting the presence of additional risk factors. 21816777 2011
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
0.050 GeneticVariation disease BEFREE Multivariate logistic regression analysis showed that CTLA4+49 allele G was positively associated with AAD (P<0.0001, odds ratio (OR)=2.43, 95% confidence interval=1.54-3.86) also after correction for DRB1*03-DQA1*0501-DQB1*0201, DRB1*04-DQA1*0301-DQB1*0302, and sex. 19884265 2010
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
0.050 Biomarker disease BEFREE Multivariate logistic regression analysis showed that MHC2TA AG+GG continued to be positively associated with genetic risk for AAD (P = 0.028, odds ratio = 1.72, 95% confidence interval = 1.06-2.78), after correction for DRB1*03-DQA1*0501-DQB1*0201, DRB1*04 (not 0403)-DQA1*0301-DQB1*0302 and DRB1*0403. 16849401 2006
Entrez Id: 129831
Gene Symbol: RBM45
RBM45
0.050 Biomarker disease BEFREE Multivariate logistic regression analysis revealed that DQ-LTR13 is not independently associated with type 1 diabetes and AAD after correction for DQB1*0302 and DRB1*0403. 15734871 2005