Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.040 GeneticVariation disease BEFREE The IDH1 mutant fibrosarcoma secretome stimulated vascular-endothelial tube formation by ~138% relative to control. 30755816 2019
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.040 GeneticVariation disease BEFREE Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Sells. 30355481 2018
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.040 GeneticVariation disease BEFREE Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cells. 28578659 2017
Entrez Id: 3417
Gene Symbol: IDH1
IDH1
0.040 GeneticVariation disease BEFREE Here, using a genetically engineered inducible system, we report that selective suppression of endogenous mutant IDH1 expression in HT1080, a fibrosarcoma cell line with a native IDH1(R132C) heterozygous mutation, significantly inhibits cell proliferation and decreases clonogenic potential. 22885298 2012