| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.090 | GeneticVariation | disease | BEFREE | We observed recurrent variants of known IBC-related mutations, and the most commonly mutated genes in DCIS were PIK3CA (34.4%) and TP53 (18.4%). | 31420779 | 2019 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | TP53 and ERBB2 mutations were significantly more prevalent in inflammatory breast cancer than in non-inflammatory breast cancer (P < 0.01). | 28243898 | 2017 | ||||
|
0.090 | Biomarker | disease | BEFREE | This study reviews the advances in molecular understanding of IBC and focuses on the efficacy of therapies that target the epidermal growth factor pathway and angiogenesis as well as early investigational therapies involving RhoC and TP53. | 20133255 | 2010 | ||||
|
0.090 | Biomarker | disease | BEFREE | Our objectives are to clarify molecular alterations of HER-2/neu and p53 in IBC and to investigate the prognostic factors. | 16755113 | 2006 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The role of p53 mutations as a prognostic factor and therapeutic target in inflammatory breast cancer. | 16563093 | 2006 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | LCIS demonstrated a low grade/favorable biophenotype that was not significantly different in cases with and without synchronous IBC (ER 98%, PgR 84%, c-erbB-24%, p53 19% and proliferation rate 2%). | 15830138 | 2005 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | We retrospectively analyze the expression of p53 as a prognostic marker to predict pathological complete response and survival in patients with IBC. | 15448010 | 2004 | ||||
|
0.090 | GeneticVariation | disease | BEFREE | The prevalence of the TP53 mutation was much higher in IBC than in the two other types of cancer (57% vs 30). | 12386822 | 2002 | ||||
|
0.090 | Biomarker | disease | BEFREE | Twenty-seven cases of inflammatory breast cancer were screened for the presence of the p53 protein by immunocytochemical methods using a monoclonal antibody directed against the p53 protein. | 1353891 | 1992 |