In conclusion, our meta-analysis suggests that two folate metabolism genetic variants MTRR rs1801394" genes_norm="4552">A66G (rs1801394) and MTHFRA1298C (rs1801131) contribute to genetic susceptibility to meningioma and glioma in adults.
The results revealed that variations of the MTHFR gene were associated with meningioma; this finding indicates that the MTHFR gene potentially plays an important role in the pathogenesis of meningioma in the Northern Chinese Han population.