×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
AlteredExpression
disease
BEFREE
CD44 attenuates activation of the hippo signaling pathway and is a prime therapeutic target for glioblastoma .
20197461
2010
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
CD44 -associated radioresistance of glioblastoma in irradiated brain areas with optimal tumor coverage.
31746135
2020
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
CD44 has been proposed as an invasion marker for glioblastoma .
9436970
1997
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
AlteredExpression
disease
BEFREE
Epithelial membrane protein 3 regulates TGF-β signaling activation in CD44 -high glioblastoma .
27527869
2017
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
AlteredExpression
disease
BEFREE
Expression of CD133 and CD44 in glioblastoma stem cells correlates with cell proliferation, phenotype stability and intra-tumor heterogeneity.
28241049
2017
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
Finally, we identify a BT-MSC population in human glioblastoma that is CD44 +CD9+CD166+ both in freshly isolated and culture-expanded cells.
24302539
2014
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
Here we show that soluble CD44 secreted from glioblastoma cells induces neuronal degeneration through the activation of tau pathology in the brain.
29622771
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
In summary, novel CD44 targeted polymeric based nanocarriers appear to be proficient in mediating site-specific delivery of quercetin via CD44 receptor in glioblastoma cells.
29030990
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
Interestingly, SWAP-70 expression was positively correlated with the expression of the standard form of CD44 (CD44 s) in GB tissues.
31832018
2019
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
MMP-9 induces CD44 cleavage and CD44 mediated cell migration in glioblastoma xenograft cells.
22024282
2012
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
AlteredExpression
disease
BEFREE
Overexpression of endogenous CD44 (cancer stem cell marker) promotes phosphorylation/inactivation of NF2, and upregulates YAP1 expression and leads to cancer cell resistance in glioblastoma .
25750037
2015
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
Regulatory factor X1 bound to the CD44 gene in glioblastoma cells.
24526308
2014
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
AlteredExpression
disease
BEFREE
Significance of Glioma Stem-Like Cells in the Tumor Periphery That Express High Levels of CD44 in Tumor Invasion, Early Progression, and Poor Prognosis in Glioblastoma .
30210550
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
AlteredExpression
disease
BEFREE
Targeting Glioblastoma Cells Expressing CD44 with Liposomes Encapsulating Doxorubicin and Displaying Chlorotoxin-IgG Fc Fusion Protein.
29495404
2018
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
TGF-β Receptor Inhibitors Target the CD44 (high)/Id1(high) Glioma-Initiating Cell Population in Human Glioblastoma .
21156287
2010
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
AlteredExpression
disease
BEFREE
TGM2 was highly expressed in CD44 -high glioblastoma tissues and tumor-derived glioma-initiating cell lines.
23877317
2013
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
AlteredExpression
disease
BEFREE
The results suggest that upregulation of NG2/CSPG4 rather than changes in CD44 or Ki-67 expression is associated with low overall survival in glioblastoma multiforme patients, supporting NG2/CSPG4 as a potential prognostic marker in glioblastoma .
28945172
2017
×
Entrez Id:
960
Gene Symbol:
CD44
CD44
0.100
Biomarker
disease
BEFREE
These results indicate that galangin is a potential novel drug for glioblastoma treatment due to its ability to suppress of CD44 , EMT and angiogenesis.
31528214
2019