Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.300 Biomarker disease MGD
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE In situ analysis of tumour specimens undergoing neovascularization show that the production of VEGF is specifically induced in a subset of glioblastoma cells distinguished by their immediate proximity to necrotic foci (presumably hypoxic regions) and the clustering of capillaries alongside VEGF-producing cells. 1279431 1992
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.300 GeneticVariation disease BEFREE A subpopulation of cells were present in the low-grade tumours that contained the same p53 gene mutation predominant in the cells of the recurrent tumours that had progressed to glioblastoma. 1311419 1992
Entrez Id: 7042
Gene Symbol: TGFB2
TGFB2
0.100 AlteredExpression disease BEFREE Unlike GM-CSF, transforming growth factor-beta 2 mRNA is expressed in ex vivo tested glioblastoma tissues. 1315829 1992
Entrez Id: 1437
Gene Symbol: CSF2
CSF2
0.080 Biomarker disease BEFREE However, there is no evidence for GM-CSF production by glioblastoma cells in vivo: fresh tumor samples lack the mRNA for GM-CSF and the protein is not detectable in the tumor cyst fluids or the cerebrospinal fluids of glioblastoma patients. 1315829 1992
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 Biomarker disease BEFREE Moreover, the presence of 15 cases of glioblastoma with loss of chromosome 10 but without EGFR gene amplification may further imply that the loss of a tumor suppressor gene (or genes) on chromosome 10 precedes EGFR gene amplification in glioblastoma tumorigenesis. 1320666 1992
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 AlteredExpression disease BEFREE Our findings suggest that the amplification and/or overexpression either of EGFR or of the alpha PDGFR along with the coordinate overexpression of the beta PDGFR can contribute to the malignant phenotype of distinct subsets of human glioblastoma. 1322795 1992
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 Biomarker disease BEFREE The loss of sequences on chromosome 10 and the deletions of 9p (that is loss of tumor suppressor genes on these locations), and epidermal growth factor receptor gene amplification, have been proposed as sequential abnormalities participating in glioblastoma tumorigenesis. 1336685 1992
Entrez Id: 2247
Gene Symbol: FGF2
FGF2
0.100 Biomarker disease BEFREE The specificity of the elevated transcription of TGF-alpha, TGF-beta, bFGF and flg in glioblastoma cell lines is further suggested by the fact that the transcription of the proto-oncogene c-erbB2, which is overproduced in breast tumor cell lines, was not elevated in glioblastoma cell lines. 1347915 1992
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.100 AlteredExpression disease BEFREE The specificity of the elevated transcription of TGF-alpha, TGF-beta, bFGF and flg in glioblastoma cell lines is further suggested by the fact that the transcription of the proto-oncogene c-erbB2, which is overproduced in breast tumor cell lines, was not elevated in glioblastoma cell lines. 1347915 1992
Entrez Id: 7039
Gene Symbol: TGFA
TGFA
0.070 AlteredExpression disease BEFREE The specificity of the elevated transcription of TGF-alpha, TGF-beta, bFGF and flg in glioblastoma cell lines is further suggested by the fact that the transcription of the proto-oncogene c-erbB2, which is overproduced in breast tumor cell lines, was not elevated in glioblastoma cell lines. 1347915 1992
Entrez Id: 3218
Gene Symbol: HOXB8
HOXB8
0.020 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3217
Gene Symbol: HOXB7
HOXB7
0.020 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3212
Gene Symbol: HOXB2
HOXB2
0.020 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3219
Gene Symbol: HOXB9
HOXB9
0.010 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3211
Gene Symbol: HOXB1
HOXB1
0.010 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3216
Gene Symbol: HOXB6
HOXB6
0.010 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3214
Gene Symbol: HOXB4
HOXB4
0.010 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3213
Gene Symbol: HOXB3
HOXB3
0.010 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3215
Gene Symbol: HOXB5
HOXB5
0.010 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3210
Gene Symbol: HOXB@
HOXB@
0.010 GeneticVariation disease BEFREE The expression of the genes in the human HOX2 locus has been studied during differentiation of two human neuroblastoma (SH-SY5Y and Kelly), a human glioblastoma (251-MG), and the murine F9 embryonal carcinoma cell lines. 1360433 1992
Entrez Id: 3815
Gene Symbol: KIT
KIT
0.070 AlteredExpression disease BEFREE Moreover, GA-17 reacted with c-kit protein expressed on the membrane of A172 human glioblastoma cells. 1370880 1992
Entrez Id: 10480
Gene Symbol: EIF3M
EIF3M
0.010 AlteredExpression disease BEFREE Moreover, GA-17 reacted with c-kit protein expressed on the membrane of A172 human glioblastoma cells. 1370880 1992
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.300 Biomarker disease BEFREE Conditional expression of wild-type (wt) p53 protein in a glioblastoma tumor cell line has been shown to be growth inhibitory. 1409626 1992
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 Biomarker disease BEFREE The Ki-67 LI was higher in the glioblastoma group with EGFR gene amplification (8 tumours, median value of Ki-67 LI 4.2, range 0.4-24.6) than in those without EGFR gene amplification (12 tumours, median value of Ki-67 LI 0.8, range 0.2-11.8) (0.05 p less than 0.1). 1414519 1992