×
Entrez Id: 28951
Gene Symbol: TRIB2
TRIB2
0.010
Biomarker
disease
BEFREE
Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma .
31318172 2020
×
Entrez Id: 8404
Gene Symbol: SPARCL1
SPARCL1
0.010
AlteredExpression
disease
BEFREE
Enhanced SPARCL1 expression in cancer stem cells improves preclinical modeling of glioblastoma by promoting both tumor infiltration and angiogenesis.
31830525 2020
×
Entrez Id: 478
Gene Symbol: ATP1A3
ATP1A3
0.010
AlteredExpression
disease
BEFREE
Gamabufotalin induces a negative feedback loop connecting ATP1A3 expression and the AQP4 pathway to promote temozolomide sensitivity in glioblastoma cells by targeting the amino acid Thr794.
31746080 2020
×
Entrez Id: 29968
Gene Symbol: PSAT1
PSAT1
0.010
Biomarker
disease
BEFREE
Regorafenib induces lethal autophagy arrest by stabilizing PSAT1 in glioblastoma .
30909789 2020
×
Entrez Id: 440275
Gene Symbol: EIF2AK4
EIF2AK4
0.010
AlteredExpression
disease
BEFREE
Our results show that GCN2 deficiency limited CD8<sup>+</sup> T-cell activation and expression of cytotoxic markers in two separate murine models of glioblastoma in vivo.
31844909 2020
×
Entrez Id: 10611
Gene Symbol: PDLIM5
PDLIM5
0.010
Biomarker
disease
BEFREE
Suppression of LIM Kinase 1 and LIM Kinase 2 Limits Glioblastoma Invasion.
31641031 2020
MAPK8IP2
0.010
GeneticVariation
disease
BEFREE
This multicenter, open-label, Phase Ib/II study included adult patients with glioblastoma with mesenchymal-epithelial transcription factor (c-Met) amplification.
31776899 2020
×
Entrez Id: 7433
Gene Symbol: VIPR1
VIPR1
0.010
Biomarker
disease
BEFREE
Targeting VPAC1 Receptors for Imaging Glioblastoma .
31292914 2020
×
Entrez Id: 894
Gene Symbol: CCND2
CCND2
0.010
Biomarker
disease
BEFREE
Prognostic impact of glioblastoma stem cell markers OLIG2 and CCND2 .
31568682 2020
×
Entrez Id: 4214
Gene Symbol: MAP3K1
MAP3K1
0.010
Biomarker
disease
BEFREE
Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma .
31318172 2020
×
Entrez Id: 4781
Gene Symbol: NFIB
NFIB
0.010
AlteredExpression
disease
BEFREE
The expression of NFIA and NFIB is reduced in glioblastoma as compared to lower grade astrocytomas.
31760595 2020
×
Entrez Id: 79623
Gene Symbol: GALNT14
GALNT14
0.010
Biomarker
disease
BEFREE
The purpose of this study was to determine the effects of IGFBP-3 and GalNAc-T14 on the proliferation and cell cycle of glioblastoma cells and to explore the mechanisms of action.
31713889 2020
HAS2-AS1
0.010
Biomarker
disease
BEFREE
Long noncoding RNA HAS2-AS1 promotes tumor progression in glioblastoma via functioning as a competing endogenous RNA.
31385362 2020
×
Entrez Id: 4245
Gene Symbol: MGAT1
MGAT1
0.010
AlteredExpression
disease
BEFREE
In summary, our findings indicate that MGAT1 is highly expressed in glioblastoma and promotes glioma cells at least partly through upregulation of Glut1 protein.
31494931 2020
×
Entrez Id: 4772
Gene Symbol: NFATC1
NFATC1
0.010
Biomarker
disease
BEFREE
NFAT2 -HDAC1 signaling contributes to the malignant phenotype of glioblastoma .31400279 2020
×
Entrez Id: 56937
Gene Symbol: PMEPA1
PMEPA1
0.010
Biomarker
disease
BEFREE
PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1.31605013 2020
FOXD1-AS1
0.010
Biomarker
disease
BEFREE
These data indicated that FOXD1-AS1 , a miR339/342 target, affected biological processes via protein eIF5a; thus, it might be considered as a new therapeutic target for glioblastoma .
31102349 2020
×
Entrez Id: 5355
Gene Symbol: PLP2
PLP2
0.010
AlteredExpression
disease
BEFREE
Reduced expression of proteolipid protein 2 increases ER stress-induced apoptosis and autophagy in glioblastoma .
31778016 2020
×
Entrez Id: 2203
Gene Symbol: FBP1
FBP1
0.010
AlteredExpression
disease
BEFREE
Decreased FBP1 expression rewires metabolic processes affecting aggressiveness of glioblastoma .
31444412 2020
×
Entrez Id: 4311
Gene Symbol: MME
MME
0.010
Biomarker
disease
BEFREE
The synergistic effect of DZ‑NEP , panobinostat and temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells.
31746375 2020
×
Entrez Id: 4774
Gene Symbol: NFIA
NFIA
0.010
AlteredExpression
disease
BEFREE
The expression of NFIA and NFIB is reduced in glioblastoma as compared to lower grade astrocytomas.
31760595 2020
×
Entrez Id: 442909
Gene Symbol: MIR342
MIR342
0.010
AlteredExpression
disease
BEFREE
As well as, Western blotting results confirmed a decrease in BCL2L1 protein following overexpression of miR-342 in glioblastoma cells.
31751869 2020
×
Entrez Id: 598
Gene Symbol: BCL2L1
BCL2L1
0.010
AlteredExpression
disease
BEFREE
As well as, Western blotting results confirmed a decrease in BCL2L1 protein following overexpression of miR-342 in glioblastoma cells.
31751869 2020
×
Entrez Id: 10858
Gene Symbol: CYP46A1
CYP46A1
0.010
Biomarker
disease
BEFREE
Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma .
31777202 2020
×
Entrez Id: 5230
Gene Symbol: PGK1
PGK1
0.010
AlteredExpression
disease
BEFREE
Analyses of human glioblastoma specimens reveals that PGK1 Y324 phosphorylation levels inversely correlate with PTEN expression status and are positively associated with poor prognosis in glioblastoma patients.
31492635 2019