| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.100 | Biomarker | disease | BEFREE | Increased Antiangiogenic Effect by Blocking CCL2-dependent Macrophages in a Rodent Glioblastoma Model: Correlation Study with Dynamic Susceptibility Contrast Perfusion MRI. | 31366997 | 2019 | ||||
|
0.100 | Biomarker | disease | BEFREE | SIGNIFICANCE: Full-length EGFR and truncated EGFRvIII work through KRAS to upregulate the chemokine CCL2 and drive macrophage infiltration in glioblastoma. | 30401716 | 2018 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | These results provide evidence that NCs induce the expression of CCL2/MCP-1 and CCL20/MIP-3α in glioblastoma cells through activation of NF-κB and AP-1 and facilitate the infiltration of microglia into tumor tissues. | 30048972 | 2018 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | OV-induced CCN1 increases macrophage migration toward infected glioblastoma cells by directly binding macrophages and also by enhancing the proinflammatory activation of macrophages inducing MCP-1 expression in glioblastoma cells. | 24895995 | 2014 | ||||
|
0.100 | Biomarker | disease | BEFREE | Our results suggested that MCP-1 is involved in the suppression of human glioblastoma cell growth by cx43. | 12019157 | 2002 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Transient transfection of an expression construct encoding the full-length Tat into the human glioblastoma-astrocytoma cell line U-87 MG enhances reporter gene activity from cotransfected deletion constructs of the MCP-1 promoter. | 10644332 | 2000 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Altered monocyte chemotactic and activating factor gene expression in human glioblastoma cell lines increased their susceptibility to cytotoxicity. | 8691078 | 1996 | ||||
|
0.100 | GeneticVariation | disease | BEFREE | The 5' untranslated region of MCP-1 gene was linked to chloramphenicol acetyl transferase (CAT) reporter gene and transfected into human glioblastoma cells in which endogenous MCP gene expression was found to be stimulated by TPA and tumor necrosis factor-alpha (TNF-alpha). | 7891669 | 1994 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Northern blot analysis demonstrated constitutive expression of MCP-1 mRNA in 6 of 12 glioblastoma cell lines. | 7517920 | 1994 | ||||
|
0.100 | AlteredExpression | disease | BEFREE | Several human astrocytoma and glioblastoma cell lines expressed high levels of IL-8 and MCAF mRNA in vitro upon stimulation with IL-1 and TNF-alpha. | 1937574 | 1991 |