Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 Biomarker disease BEFREE Here we demonstrate that IL-10 was specifically induced by the EBV-latent membrane protein 1 (LMP1) in Burkitt's lymphoma (BL) cell lines BL2 and BL41. 11162833 2001
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 Biomarker disease BEFREE EBER induces IL-10 and thus supports the growth of Burkitt's lymphoma (BL) cells. 18362887 2008
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 Biomarker disease BEFREE The Epstein-Barr virus latent membrane protein-1 (LMP1) induces interleukin-10 production in Burkitt lymphoma lines. 8157362 1994
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 Biomarker disease BEFREE These results suggest that IL-10 induced by EBERs acts as an autocrine growth factor for BL. 11118209 2000
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 AlteredExpression disease BEFREE Furthermore, EBERs induce transcription of interleukin-10, which acts as an autocrine growth factor of BL. 11669608 2001
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 GeneticVariation disease BEFREE IL10 -1082GG and GCC/GCC genotypes were more frequent in patients than in controls, and associated to a higher risk of BL development (GG genotype OR 2.62, 95% CI, 1.25-5.51; P = 0.008; Pc = 0.024). 23029361 2012
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 Biomarker disease BEFREE Using a wide panel of EBV positive and EBV negative cell lines, it has been shown that EBV positive B cell lines derived from patients with AIDS and Burkitt's lymphoma (AABCL) secrete large quantities of B cell IL-10, compared with EBV-positive B cell lines obtained from patients with undifferentiated lymphomas of Burkitt's and non-Burkitt's types. 8167552 1994
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 AlteredExpression disease BEFREE IL-10 can induce the expression of EBV-encoded latent membrane protein-1 (LMP-1) in the absence of EBNA-2 in B lymphocytes and in Burkitt lymphoma- and NK lymphoma-derived cell lines. 16332968 2006
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 PosttranslationalModification disease BEFREE Isolation of the human interleukin 10 promoter. Characterization of the promoter activity in Burkitt's lymphoma cell lines. 7749063 1995
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 Biomarker disease BEFREE In this study we have successfully quantified elevated expressional levels of both cellular and viral transcripts, namely EBER1, EBER2 and anti-inflammatory cytokine (IL-10) in the FFPE Burkitt's lymphoma (BL) specimens of Pakistani origin. 21791113 2011
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 Biomarker disease BEFREE Human B-cell interleukin-10: B-cell lines derived from patients with acquired immunodeficiency syndrome and Burkitt's lymphoma constitutively secrete large quantities of interleukin-10. 1325212 1992
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.100 AlteredExpression disease BEFREE Upon superinfection with non-defective EBV, the EBV-negative cell line BL 41 up-regulated IL-10 expression. 7694007 1993