Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 GeneticVariation disease BEFREE In B-cell NHL, specific translocations and oncogene rearrangements are associated with specific NHL subtypes de novo; many of these translocations involve immunoglobulin genes, such as t(14;18) in follicular lymphoma, t(11;14) in MCL, t(3;14) in DLLC, and t(8;14) in Burkitt's lymphoma. 9720711 1998
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 GeneticVariation disease BEFREE Recurrent RHOA mutations in pediatric Burkitt lymphoma treated according to the NHL-BFM protocols. 25044415 2014
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 GeneticVariation disease BEFREE In conclusion, the miRs expression in B-NHLs[11q] provides a new suggestion, in addition to pathomorphological and clinical similarities between classical, i.e., MYC translocation-positive BL, and B-NHLs[11q], to recognize the B-NHLs[11q] subgroup of DLBCL/BL category as a MYC translocation-negative variant of BL in most cases, and points to the potential utility of miR-155/BIC/miR-21/miR-26a for the differential diagnosis of a heterogeneous category of DLBCL/BL. 25677902 2015
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 Biomarker disease BEFREE A chromosomal translocation (Tx) that interrupts the transcription of either c-Myc or Pvt 1 is the principal lesion in many B cell malignancies including Burkitt's Lymphoma (BL), AIDs-NHL, mouse plasmacytoma (Pct) and possibly multiple myeloma (MM). 9308229 1997
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 Biomarker disease BEFREE The vast majority of systemic AIDS-NHL belongs to 3 high-grade B-cell lymphomas: Burkitt's lymphoma (BL), immunoblastic lymphoma (IBL), and large-cell lymphoma (LCL). 12055673 2002
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 Biomarker disease BEFREE Burkitt lymphoma accounts for approximately 50% of pediatric cancers in equatorial Africa and a majority of NHL in Uganda. 21127431 2011
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 Biomarker disease BEFREE Induction of lytic cycle highlighted by the expression of BZLF1 occurred in 55.5% of PTLD, 36% of LC/IB and 22% of BL AR-NHL. 8172807 1994
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 AlteredExpression disease BEFREE Pre-clinical pharmacology of AZD3965, a selective inhibitor of MCT1: DLBCL, NHL and Burkitt's lymphoma anti-tumor activity. 29050199 2017
Entrez Id: 51750
Gene Symbol: RTEL1
RTEL1
0.090 AlteredExpression disease BEFREE Two of the Vkappa sequences of BL and two of those of the B-NHL were heavily mutated (up to 11%), when compared with their closest germline variable region counterparts ("clonal mutations"). 10485273 1999