Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.090 | Biomarker | disease | BEFREE | CD154 tone sets the signaling pathways and transcriptome generated in model CD40-pluricompetent L3055 Burkitt's lymphoma cells. | 17709483 | 2007 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | We report here that CD40-induced TRAF3-dependent activation of mitogen-activated protein kinase (MAPK)/extracellular signal-regulated kinase (ERK) kinase 1 (MEK1) is involved in the upregulation of IL-4-driven germline C epsilon transcription in a human Burkitt's lymphoma B cell line, DG75. | 12220533 | 2002 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | Ketoconazole also inhibited interleukin-4 plus anti-CD40-induced activation of germline epsilon promoter in human Burkitt lymphoma Ramos cells. | 12230500 | 2002 | ||||
|
0.090 | Biomarker | disease | BEFREE | When immunodeficient mice bearing Burkitt lymphoma were treated with srhCD40L, significant increases in survival were observed indicating a direct antitumor effect as a result of CD40 stimulation in vivo. | 12070030 | 2002 | ||||
|
0.090 | Biomarker | disease | BEFREE | We conclude that some BL cell lines show a highly restricted response to CD40 ligation but remain fully susceptible to LMP1. | 10092782 | 1999 | ||||
|
0.090 | Biomarker | disease | BEFREE | CD40 cross-linking enhances the immunogenicity of Burkitt's-lymphoma cell lines. | 10597194 | 1999 | ||||
|
0.090 | AlteredExpression | disease | BEFREE | We report here that the signaling cascade triggered by interleukin-4 (IL-4) or anti-CD40 monoclonal antibody (mAb) participates in NF-kappa B activation responsible for germline C epsilon transcription in a human Burkitt lymphoma B cell line, DND39. | 9070319 | 1997 | ||||
|
0.090 | Biomarker | disease | BEFREE | Modulation of vimentin, the CD40 activation antigen and Burkitt's lymphoma antigen (CD77) by the Epstein-Barr virus nuclear antigen EBNA-4. | 8009829 | 1994 | ||||
|
0.090 | Biomarker | disease | BEFREE | Burkitt's lymphoma and Epstein-Barr virus-transformed B cell lines and tonsilar B lymphocytes were treated with the anti-CD40 mAb for various lengths of time. | 7515102 | 1994 |