Gene: MIR221 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 407006
Gene Symbol: MIR221
MIR221 		0.070 Biomarker disease BEFREE A former study revealed that microRNA-221 (miR-221) was involved in cell proliferation of liver cancer and HCC development. 30370582 2019
Entrez Id: 407006
Gene Symbol: MIR221
MIR221 		0.070 Biomarker disease BEFREE However, the role of miR-221 in human liver cancer progression is not yet fully elucidated. 31214616 2019
Entrez Id: 407006
Gene Symbol: MIR221
MIR221 		0.070 Biomarker disease BEFREE The miR-221-3p/miR-15b-5p-Axin2 axis may serve as a therapeutic target in patients with liver cancer. 31814849 2019
Entrez Id: 407006
Gene Symbol: MIR221
MIR221 		0.070 Biomarker disease BEFREE Oroxin B Induces Apoptosis by Down-Regulating MicroRNA-221 Resulting in the Inactivation of the PTEN/PI3K/AKT Pathway in Liver Cancer. 31801250 2019
Entrez Id: 407006
Gene Symbol: MIR221
MIR221 		0.070 Biomarker disease BEFREE These data suggested the potential of combining AAV-TRAIL with miR-221-Zip as a therapeutic intervention for liver cancer. 28900506 2017
Entrez Id: 407006
Gene Symbol: MIR221
MIR221 		0.070 Biomarker disease BEFREE Oncomirs miRNA-221/222 and Tumor Suppressors miRNA-199a/195 Are Crucial miRNAs in Liver Cancer: A Systematic Analysis. 27156077 2016
Entrez Id: 407006
Gene Symbol: MIR221
MIR221 		0.070 Biomarker disease BEFREE In conclusion, we showed that miR-221 is a critical modulator in the HCC signaling pathway, and miR-221 silencing inhibits liver cancer malignant properties in vitro and in vivo, which may benefit the treatment for patients with unresectable HCC. 24993451 2014