Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		0.400 GeneticVariation disease BEFREE 36 (57%) had oligodendroglioma and 27 astrocytoma.IDH-1 mutation was present in 53 (84%). 30292978 2018
Entrez Id: 1326
Gene Symbol: MAP3K8
MAP3K8 		0.010 AlteredExpression disease BEFREE 5 (an EST) was more expressed by GDA analysis in histologically normal adjacent brain tissue than in the corresponding oligodendroglioma. 11172594 2001
Entrez Id: 6783
Gene Symbol: SULT1E1
SULT1E1 		0.010 AlteredExpression disease BEFREE 5 (an EST) was more expressed by GDA analysis in histologically normal adjacent brain tissue than in the corresponding oligodendroglioma. 11172594 2001
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.010 AlteredExpression disease BEFREE Tumor necrosis factor modulates transcription of myelin basic protein gene through nuclear factor kappa B in a human oligodendroglioma cell line. 12175864 2002
Entrez Id: 1641
Gene Symbol: DCX
DCX 		0.010 AlteredExpression disease BEFREE DCX was highly expressed in both high-grade invasive tumors (glioblastoma, n=11; anaplastic astrocytoma/oligoastrocytoma, n=7; and medulloblastoma/PNET, n=6) and low-grade invasive tumors (oligodendroglioma, n=3; and astrocytoma/oligoastrocytoma, n=5). 16195916 2005
Entrez Id: 27165
Gene Symbol: GLS2
GLS2 		0.010 AlteredExpression disease BEFREE LGA mRNA was also relatively high in ganglioglioma which contains a discernable proportion of neuronal cells, and in oligodendroglioma. 17940881 2008
Entrez Id: 3956
Gene Symbol: LGALS1
LGALS1 		0.010 Biomarker disease BEFREE Galectin 1 has been shown to be involved in Hs683 oligodendroglioma chemoresistance, neoangiogenesis, and migration. 19412433 2009
Entrez Id: 92140
Gene Symbol: MTDH
MTDH 		0.010 Biomarker disease BEFREE AEG-1 might represent a novel, useful diagnostic and prognostic marker for oligodendroglioma and play a role during the development and progression of the disease. 20236756 2010
Entrez Id: 596
Gene Symbol: BCL2
BCL2 		0.030 Biomarker disease BEFREE Bcl-2 promotes malignant progression in a PDGF-B-dependent murine model of oligodendroglioma. 21171016 2011
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.050 AlteredExpression disease BEFREE EGFR expression stratifies oligodendroglioma behavior. 21839716 2011
Entrez Id: 9118
Gene Symbol: INA
INA 		0.020 AlteredExpression disease BEFREE Alpha internexin expression related with molecular characteristics in adult glioblastoma and oligodendroglioma. 23579442 2013
Entrez Id: 3560
Gene Symbol: IL2RB
IL2RB 		0.010 AlteredExpression disease BEFREE Interleukin 2 receptor beta chain expressed in an oligodendroglioma line binds interleukin 2 and delivers growth signal. 2395860 1990
Entrez Id: 47
Gene Symbol: ACLY
ACLY 		0.010 GeneticVariation disease BEFREE ACLY or phospho-ACLY were similarly reduced in CIC-mutant 1p19q co-deleted oligodendroglioma patient samples. 25277207 2014
Entrez Id: 110806263
Gene Symbol: LOC110806263
LOC110806263 		0.020 GeneticVariation disease BEFREE TERT promoter mutations were highly frequent in glioblastoma (83.9%), urothelial carcinoma (64.5%), oligodendroglioma (70.0%), medulloblastoma (33.3%) and hepatocellular carcinoma (31.4%). 25843513 2015
Entrez Id: 5777
Gene Symbol: PTPN6
PTPN6 		0.010 Biomarker disease BEFREE PTPN6 and CUL3 were the key hub genes identified in the astrocytoma relative to the oligodendroglioma. 28924174 2017
Entrez Id: 23152
Gene Symbol: CIC
CIC 		0.070 GeneticVariation disease BEFREE CIC loss-of-function mutations are frequently observed in several human neoplasms such as oligodendroglioma, and lung and gastric carcinoma. 28985030 2017
Entrez Id: 29998
Gene Symbol: BICRA
BICRA 		0.020 Biomarker disease BEFREE Glioma tumor suppressor candidate region gene 1 (GLTSCR1) is associated with the progression of oligodendroglioma. 30405818 2018
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.050 GeneticVariation disease BEFREE BRAF V600E mutant oligodendroglioma-like tumors with chromosomal instability in adolescents and young adults. 31630459 2019
Entrez Id: 673
Gene Symbol: BRAF
BRAF 		0.050 GeneticVariation disease BEFREE A BRAF(V600E) mutation was also detected in one oligodendroglioma, and a BRAF(A598V) in one diffuse astrocytoma. 22568401 2012
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		0.400 GeneticVariation disease BEFREE A better prognosis was significantly associated with combined IDH1 mutation and MGMT methylation status (both positive vs both negative, HR 0.079 [95% CI 0.008-0.579], p=0.012), as well as histology (OG vs DA and OA, HR 0.158 [95% CI 0.022-0.674], p=0.011) and tumor size (<6 cm vs ≥6 cm, HR 0.120 [95% CI 0.017-0.595], p=0.008). 26276726 2015
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.060 GeneticVariation disease BEFREE A better prognosis was significantly associated with combined IDH1 mutation and MGMT methylation status (both positive vs both negative, HR 0.079 [95% CI 0.008-0.579], p=0.012), as well as histology (OG vs DA and OA, HR 0.158 [95% CI 0.022-0.674], p=0.011) and tumor size (<6 cm vs ≥6 cm, HR 0.120 [95% CI 0.017-0.595], p=0.008). 26276726 2015
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.400 GeneticVariation disease BEFREE A c.515G>T (p.R172M) mutation of the IDH2 gene was only identified in a grade II oligodendroglioma patient which was wild-type for IDH1. 21643842 2011
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		0.400 GeneticVariation disease BEFREE A c.515G>T (p.R172M) mutation of the IDH2 gene was only identified in a grade II oligodendroglioma patient which was wild-type for IDH1. 21643842 2011
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		0.400 GeneticVariation disease BEFREE A total of 135 cases consisted of 38 IDH-mutant [17 astrocytoma (AC), 13 oligodendroglioma (OD) and eight glioblastoma (GBM)], 87 IDH-wildtype (six AC, three OD and 78 GBM), and 10 diffuse midline glioma, H3K27M-mutant. 30710203 2019
Entrez Id: 3418
Gene Symbol: IDH2
IDH2 		0.400 GeneticVariation disease BEFREE A total of 135 cases consisted of 38 IDH-mutant [17 astrocytoma (AC), 13 oligodendroglioma (OD) and eight glioblastoma (GBM)], 87 IDH-wildtype (six AC, three OD and 78 GBM), and 10 diffuse midline glioma, H3K27M-mutant. 30710203 2019