Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6493
Gene Symbol: SIM2
SIM2
0.010 Biomarker disease BEFREE SIM2 knockdown in CvSCC cell lines showed resistance to hypoxia with increased expression of HIF1A and its target genes. 29109451 2017
Entrez Id: 442918
Gene Symbol: MIR373
MIR373
0.010 Biomarker disease BEFREE MiRNA373 and scramble miRNA were synthetized and transfected to cervical squamous cell carcinoma SiHa cells by lipofectamine. 29125482 2018
Entrez Id: 4072
Gene Symbol: EPCAM
EPCAM
0.010 AlteredExpression disease BEFREE EpCAM expression in squamous cell carcinoma of the uterine cervix detected by monoclonal antibody to the membrane-proximal part of EpCAM. 29202724 2017
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.060 GeneticVariation disease BEFREE ERBB2 mutation: A promising target in non-squamous cervical cancer. 29279289 2018
Entrez Id: 9927
Gene Symbol: MFN2
MFN2
0.010 Biomarker disease BEFREE MFN2 may be involved in cervical cancer pathogenesis as an oncogene and might serve as a biomarker of cervical SCC. 29848692 2018
Entrez Id: 6280
Gene Symbol: S100A9
S100A9
0.010 Biomarker disease BEFREE S100A9 regulates cisplatin chemosensitivity of squamous cervical cancer cells and related mechanism. 30288106 2018
Entrez Id: 4690
Gene Symbol: NCK1
NCK1
0.010 AlteredExpression disease BEFREE Nck1 level gradually increased from normal cervical epithelia to high-grade CIN, overexpressed in CSCC and was associated with cancer MVD. 30442385 2019
Entrez Id: 8986
Gene Symbol: RPS6KA4
RPS6KA4
0.010 Biomarker disease BEFREE MSK2 promotes proliferation and tumor formation in squamous cervical cancer via PAX8/RB-E2F1/cyclin A2 axis. 30756420 2019
Entrez Id: 1182
Gene Symbol: CLCN3
CLCN3
0.010 AlteredExpression disease BEFREE ClC-3 mRNA and protein expression in SCC tissues from cervical squamous cell carcinoma patients was significantly upregulated, and no significant difference was noted between the matched paracarcinoma fresh tissue from the same patients and non-cervical cancer patients. 30905432 2019
Entrez Id: 2056
Gene Symbol: EPO
EPO
0.010 AlteredExpression disease BEFREE EPO and EPO-R expression were not significantly associated with clinicopathological parameters of CSCC patients (<i>P</i>>0.05). 30915348 2019
Entrez Id: 574030
Gene Symbol: MIR362
MIR362
0.010 PosttranslationalModification disease BEFREE MiR-362-3p is downregulated by promoter methylation and independently predicts shorter OS of cervical squamous cell carcinoma. 31082771 2019
Entrez Id: 7099
Gene Symbol: TLR4
TLR4
0.020 AlteredExpression disease BEFREE TLR4,7 demonstrated low expression in CSCC. 31375269 2019
Entrez Id: 1755
Gene Symbol: DMBT1
DMBT1
0.010 Biomarker disease BEFREE DMBT1 was decreased in CSCC, whereas its overexpression can not only inhibit the proliferation, migration, and invasion, but induce the apoptosis of human CSCC cells, being a novel strategy for CSCC treatment. 31400059 2019
Entrez Id: 116833
Gene Symbol: ANIB1
ANIB1
0.010 Biomarker disease BEFREE AIB1 predicts tumor response to definitive chemoradiotherapy and prognosis in cervical squamous cell carcinoma. 31602272 2019
Entrez Id: 8202
Gene Symbol: NCOA3
NCOA3
0.010 Biomarker disease BEFREE AIB1 predicts tumor response to definitive chemoradiotherapy and prognosis in cervical squamous cell carcinoma. 31602272 2019
Entrez Id: 6282
Gene Symbol: S100A11
S100A11
0.010 AlteredExpression disease BEFREE S100A11 expression was positively correlated with the FIGO stage and lymph node metastasis of CSCC patients (P < 0.05). 31695426 2019
Entrez Id: 53905
Gene Symbol: DUOX1
DUOX1
0.010 AlteredExpression disease BEFREE DUOX1 and NOX2 expression are associated with mucosal immunity activated in cervical squamous cell carcinoma and predicts a favorable prognosis in cervical cancer patients. 31706280 2019
Entrez Id: 57291
Gene Symbol: DANCR
DANCR
0.010 Biomarker disease BEFREE LncRNA ANCR and hypoxia‑inducible factor 1α (HIF‑1α) expression vectors were constructed and transfected into CSCC cell lines, and cell proliferation under normal O2 and hypoxic conditions (8% O2) was detected using a Cell Counting kit‑8 assay. 31746351 2020
Entrez Id: 9547
Gene Symbol: CXCL14
CXCL14
0.020 AlteredExpression disease BEFREE CXCL14 was a significantly under-expressed mRNA in hepatocellular carcinoma tissues according to our microarray analysis, as well as head and neck squamous cell carcinoma and cervical squamous cell carcinoma. 31849533 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.060 Biomarker disease BEFREE ERBB2 (HER2/neu) oncogene is frequently amplified in squamous cell carcinoma of the uterine cervix. 7905784 1994
Entrez Id: 5744
Gene Symbol: PTHLH
PTHLH
0.010 AlteredExpression disease BEFREE PTH-rP mRNA levels were evaluated by Northern analysis in A431 cells (derived from a human vulvar epidermoid carcinoma) and ME-180 cells (derived from a human papillomavirus-infected squamous cell carcinoma of the cervix). 8111720 1994
Entrez Id: 693227
Gene Symbol: MIR642A
MIR642A
0.010 AlteredExpression disease BEFREE A 2-miRNA expression signature of hsa-mir-642a and hsa-mir-378c associated with survivability was identified in CSCC. 29513728 2018
Entrez Id: 100422867
Gene Symbol: MIR378C
MIR378C
0.010 AlteredExpression disease BEFREE A 2-miRNA expression signature of hsa-mir-642a and hsa-mir-378c associated with survivability was identified in CSCC. 29513728 2018
Entrez Id: 8190
Gene Symbol: MIA
MIA
0.010 Biomarker disease BEFREE A comprehensive expression analysis of the MIA gene family in malignancies: MIA gene family members are novel, useful markers of esophageal, lung, and cervical squamous cell carcinoma. 27145272 2016
Entrez Id: 309
Gene Symbol: ANXA6
ANXA6
0.010 AlteredExpression disease BEFREE A differential protein pattern for SCC was, e.g. over-expressed (OE) eukaryotic translation initiation factor 3-2β, neutrophil cytosolic factor 2, annexin A6 (ANXA6), for SVC it was OE cathepsin D, γ-catenin, RAB2A, for both cancers it was OE apolipoprotein E, tropomyosin 3, HSPA8, and underexpressed cytokeratin 13, osteoglycin. 21137014 2010