Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.060 AlteredExpression disease BEFREE The PI3K/AKT/mTOR signaling pathway is frequently activated in HPV-positive cervical squamous cell cancer (CC). 29103764 2018
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.060 Biomarker disease BEFREE In summary, DEPTOR is found to promote survival of cervical SCC cells and its reduction induced apoptosis via differential effects on PI3K/AKT and p38 MAPK and can be a potential target in cervical SCC. 26992219 2016
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.060 GeneticVariation disease BEFREE Additional genomic alterations, independent of integration events, include recurrent PIK3CA mutations (and aberrations in other members of the PI3K pathway), alterations in receptor tyrosine kinases (primarily FGFR2 and FGFR3 in HPV-positive HNSCC, and ERBB2 in cervical squamous cell carcinoma), and genes in pathways related to squamous cell differentiation and immune responses. 25779941 2015
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.060 Biomarker disease BEFREE The relatively high PIK3CA mutation rates indicate that PI3K may be a therapeutic target for a significant subset of CSCC patients. 26209091 2015
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.060 GeneticVariation disease BEFREE The objective of this study was to investigate the predictive value of common genetic alterations of PI3K/AKT/mTOR and Ras/Raf/MAPK pathways in patients with locally advanced cervical squamous cell carcinoma (LACSCC) treated with cisplatin-based concurrent chemoradiotherapy (CCRT). 25773678 2015
Entrez Id: 5291
Gene Symbol: PIK3CB
PIK3CB
0.060 GeneticVariation disease BEFREE The objective of this study was to evaluate the association between genetic polymorphisms in the PI3K/Akt pathway and chemotherapeutic outcomes following platinum-based NAC in Northwestern Chinese Han patients with squamous cervical cancer (SCC). 26585822 2015