Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.420 CausalMutation disease CGI
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.420 GeneticVariation disease BEFREE K-RAS mutation in transitional cell carcinoma of urinary bladder. 12092657 2001
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.420 GeneticVariation disease BEFREE The BRAF and KRAS gene mutations were never described before in pediatric UC. 31620413 2019
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.420 Biomarker disease HPO
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.420 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
Entrez Id: 613
Gene Symbol: BCR
BCR
0.300 GeneticVariation disease UNIPROT
Entrez Id: 2321
Gene Symbol: FLT1
FLT1
0.300 GeneticVariation disease UNIPROT
Entrez Id: 5979
Gene Symbol: RET
RET
0.300 GeneticVariation disease UNIPROT
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE Protein expression and gene copy number analysis of topoisomerase 2alpha, HER2 and P53 in minimally invasive urothelial carcinoma of the urinary bladder--a multitissue array study with prognostic implications. 15816547 2005
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE We conclude that, in contrast to immunohistochemical accumulation, gene alterations play only a minor role in tumor recurrence of p53 in patients with superficial transitional cell carcinoma of the bladder, and that immunohistochemical accumulation of the p53 protein has to be explained by mechanisms other than gene mutations. 11223675 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE Relationship of genetic instability with immunoreactivities for p53 protein and proliferating cell nuclear antigen in transitional cell carcinoma of the bladder. 8854073 1996
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE Two bladder urothelial carcinoma cell lines were used: RT4 (wild-type TP53 gene) and T24 (mutated TP53 gene). 28229968 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE TGF-betaRII, BAX, IGFIIR, caspase-5, hMSH3 and hMSH6 alterations are not associated with microsatellite instability or p53 mutations in invasive urothelial carcinoma of the urinary bladder. 17676485 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE The best documented factors involved in urinary bladder transitional cell carcinoma (TCC) are ras proto-oncogene activation and p53 suppressor gene mutations. 10079253 1999
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE The expression pattern of PAX5 in the tissue of superficial bladder transitional cell carcinoma (TCC), its prognostic value and its correlation with p53 immunohistochemistry and p53 mutation analysis were evaluated. 14577491 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE To determine prognostic factors for survival in bladder transitional cell carcinoma (TCC), and the prognostic value of p53 and ki67. 12074407 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE CHK1 and p53 demonstrated a positive correlation in BUC, and both were positively associated with the histological grade, clinical pathological staging, lymphatic metastasis and the 5-year survival rate (P<0.05). 29391889 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 GeneticVariation disease BEFREE Implications of p53 gene mutations on patient survival in transitional cell carcinoma of the bladder: a long-term study. 18367096 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE In addition to immunohistochemical and single strand conformational polymorphism analysis, we performed 3-D p53 protein modeling and correlated our results with the disease-free survival of patients with muscle invasive transitional cell carcinoma of the bladder who underwent surgery. 11696726 2001
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE We outline the basic constitutive functions of p53 and summarize its current role in the management of transitional cell carcinoma of the bladder. 12629332 2003
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 AlteredExpression disease BEFREE Over-expression of p53 nuclear oncoprotein in transitional-cell bladder cancer and its prognostic value. 8428790 1993
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 AlteredExpression disease BEFREE The expression of p53 and bcl-2 in superficial bladder transitional cell carcinoma and its role in the outcome of postoperative intravesical chemotherapy. 9891547 1999
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE The objective of the present study was to determine whether immunohistochemical staining for p53 was predictive of lymph node metastases in early muscle invasive transitional cell bladder cancer. 10606186 1999
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE Eighty-seven transitional cell carcinoma of the bladder were analyzed by immunohistochemistry (IHC) for p53 nuclear accumulation, and the results compared to mutations detected in the p53 gene evaluated by polymerase chain reaction single-strand conformation polymorphism (SSCP) and DNA sequence analysis. 10675477 2000
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200 Biomarker disease BEFREE Role of TP53 in repair of N-(deoxyguanosin-8-yl)-4-aminobiphenyl adducts in human transitional cell carcinoma of the urinary bladder. 11159753 2001