Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 23411
Gene Symbol: SIRT1
SIRT1
0.010 Biomarker disease BEFREE Further immunohistochemical and molecular evaluations are required to explore the mechanism of action of SIRT1 and to investigate molecular downstream of this potential biomarker in UCB. 31219487 2019
Entrez Id: 3620
Gene Symbol: IDO1
IDO1
0.010 Biomarker disease BEFREE One hundred and sixty paraffin-embedded UC tissues (130 bladder, 30 upper urinary tract) and 47 adjacent normal tissues were retrieved for IDO1 immunostaining. 31253481 2019
Entrez Id: 4609
Gene Symbol: MYC
MYC
0.010 Biomarker disease BEFREE A gene expression profiling chip analysis in T24 cells showed that the MYC gene may be an important downstream target of the ERH gene, and the functional experiments showed that MYC is a functional target of ERH in BUC T24 cells. 30866868 2019
Entrez Id: 51397
Gene Symbol: COMMD10
COMMD10
0.010 Biomarker disease BEFREE All the tumor tissues except breast small cell carcinoma, breast phyllodes tumor, lung adenocarcinoma, thymoma, cervical cancer and bladder urothelial carcinoma showed that COMMD10 was positive staining in cytoplasm. 30787448 2019
Entrez Id: 1580
Gene Symbol: CYP4B1
CYP4B1
0.010 AlteredExpression disease BEFREE The objective of this study was to examine the expression level of cytochrome P450 4B1 (CYP4B1) protein and its clinical significance in specimens from patients with urothelial carcinomas (UC) including upper tract urothelial carcinoma (UTUC, n = 340) and urinary bladder urothelial carcinoma (UBUC, n = 295). 30803053 2019
Entrez Id: 728192
Gene Symbol: LINC00460
LINC00460
0.010 AlteredExpression disease BEFREE TCGA data indicated that LINC00460 expression was negatively correlated with a positive prognosis in patients with bladder urothelial carcinoma (P<0.05). 30881506 2019
Entrez Id: 2079
Gene Symbol: ERH
ERH
0.010 Biomarker disease BEFREE A gene expression profiling chip analysis in T24 cells showed that the MYC gene may be an important downstream target of the ERH gene, and the functional experiments showed that MYC is a functional target of ERH in BUC T24 cells. 30866868 2019
Entrez Id: 354
Gene Symbol: KLK3
KLK3
0.010 Biomarker disease BEFREE To define a more precise PSA nadir value, we estimated serum PSA after cystoprostatectomy in cases with bladder urothelial cancer and no evidence of prostate cancer. 31004342 2019
Entrez Id: 641638
Gene Symbol: SNHG6
SNHG6
0.010 Biomarker disease BEFREE However, little is known about the molecular mechanism of SNHG6-mediated bladder urothelial carcinoma cell migration and invasion. 30168179 2019
Entrez Id: 9520
Gene Symbol: NPEPPS
NPEPPS
0.010 Biomarker disease BEFREE To define a more precise PSA nadir value, we estimated serum PSA after cystoprostatectomy in cases with bladder urothelial cancer and no evidence of prostate cancer. 31004342 2019
Entrez Id: 10181
Gene Symbol: RBM5
RBM5
0.010 AlteredExpression disease BEFREE In this study, we found that RBM5 expression was significantly down-regulated in BUC tissues when compared with the adjacent nontumor tissues. 31318608 2019
Entrez Id: 5324
Gene Symbol: PLAG1
PLAG1
0.010 Biomarker disease BEFREE To define a more precise PSA nadir value, we estimated serum PSA after cystoprostatectomy in cases with bladder urothelial cancer and no evidence of prostate cancer. 31004342 2019
Entrez Id: 1116
Gene Symbol: CHI3L1
CHI3L1
0.010 AlteredExpression disease BEFREE Kaplan-Meier survival analysis revealed that patients with high CHI3L1 expression had shorter DSS and MFS in both UTUC and UBUC (all P < 0.05). 30660494 2019
Entrez Id: 4174
Gene Symbol: MCM5
MCM5
0.010 AlteredExpression disease BEFREE Immunocytochemistry with p53, MCM5 and Ki-67 antibodies can improve the diagnostic power of urinary cytology in the detection and follow-up of urinary bladder urothelial carcinoma. 30943322 2019
Entrez Id: 5627
Gene Symbol: PROS1
PROS1
0.010 Biomarker disease BEFREE To define a more precise PSA nadir value, we estimated serum PSA after cystoprostatectomy in cases with bladder urothelial cancer and no evidence of prostate cancer. 31004342 2019
Entrez Id: 11148
Gene Symbol: HHLA2
HHLA2
0.010 AlteredExpression disease BEFREE Immunohistochemical staining showed that the expression of HHLA2 was significantly upregulated in BUC tissues compared with normal bladder tissues. 30602154 2019
Entrez Id: 7153
Gene Symbol: TOP2A
TOP2A
0.010 AlteredExpression disease BEFREE We found TOP2A was significantly upregulated in BLCA samples, especially for high-grade and advanced stage tumors, compared with matched normal epithelial tissue. 31216997 2019
Entrez Id: 29968
Gene Symbol: PSAT1
PSAT1
0.010 Biomarker disease BEFREE To define a more precise PSA nadir value, we estimated serum PSA after cystoprostatectomy in cases with bladder urothelial cancer and no evidence of prostate cancer. 31004342 2019
Entrez Id: 55722
Gene Symbol: CEP72
CEP72
0.010 AlteredExpression disease BEFREE Overexpression of CEP72 Promotes Bladder Urothelial Carcinoma Cell Aggressiveness via Epigenetic CREB-Mediated Induction of SERPINE1. 30953603 2019
Entrez Id: 8720
Gene Symbol: MBTPS1
MBTPS1
0.010 AlteredExpression disease BEFREE Differential expression of S1P receptor subtypes in human bladder transitional cell carcinoma. 30712233 2019
Entrez Id: 2875
Gene Symbol: GPT
GPT
0.010 Biomarker disease BEFREE De Ritis Ratio (Aspartate Transaminase/Alanine Transaminase) as a Significant Prognostic Factor in Patients Undergoing Radical Cystectomy with Bladder Urothelial Carcinoma: A Propensity Score-Matched Study. 31534562 2019
Entrez Id: 8361
Gene Symbol: H4C6
H4C6
0.010 AlteredExpression disease BEFREE HIST4H4 expression level was evidently up-regulated and positively correlated with AC010168.2 in BLCA patients. 30359990 2018
Entrez Id: 4486
Gene Symbol: MST1R
MST1R
0.010 AlteredExpression disease BEFREE The rate of positive RON expression differed significantly between bladder urothelial cancer tissues (54.7%) and paraneoplastic tissues (29.4%) (P<0.05). 29725403 2018
Entrez Id: 161835
Gene Symbol: FSIP1
FSIP1
0.010 AlteredExpression disease BEFREE In bladder cancer, FSIP1 overexpression was associated with poor prognosis of bladder urothelial carcinoma. 29670371 2018
Entrez Id: 79026
Gene Symbol: AHNAK
AHNAK
0.010 Biomarker disease BEFREE In conclusion, this study identified a new biomarker, AHNAK, applicable to discrimination between BLCA and BUL by LBC. 29950347 2018