Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 79719
Gene Symbol: AAGAB
AAGAB 		0.100 Biomarker disease HPO
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		0.040 Biomarker disease BEFREE <b>Conclusion</b>: The expression of miR-101-3p is positively related to CDDP sensitivity of BUC, miR-101-3p advances sensitivity of BUC to CDDP through targeted silencing EZH2. 31258770 2019
Entrez Id: 595
Gene Symbol: CCND1
CCND1 		0.030 Biomarker disease BEFREE Transitional cell carcinoma of the bladder may utilize another pathway for proliferation that is independent of cyclin D1. 9720584 1998
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.010 Biomarker disease BEFREE Interleukin-2 gene transfer into human transitional cell carcinoma of the urinary bladder. 10070868 1999
Entrez Id: 27306
Gene Symbol: HPGDS
HPGDS 		0.020 GeneticVariation disease BEFREE Glutathione S-transferase null genotypes in transitional cell bladder cancer: a case-control study. 10828664 2000
Entrez Id: 3845
Gene Symbol: KRAS
KRAS 		0.420 GeneticVariation disease BEFREE K-RAS mutation in transitional cell carcinoma of urinary bladder. 12092657 2001
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.200 AlteredExpression disease BEFREE HER2/neu overexpression in the development of muscle-invasive transitional cell carcinoma of the bladder. 14520464 2003
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.200 AlteredExpression disease BEFREE HER-2/neu protein overexpression and gene amplification in human transitional cell carcinoma of the bladder. 15072912 2004
Entrez Id: 3565
Gene Symbol: IL4
IL4 		0.010 GeneticVariation disease BEFREE Interleukin-4 gene intron-3 polymorphism is associated with transitional cell carcinoma of the urinary bladder. 15679809 2005
Entrez Id: 5079
Gene Symbol: PAX5
PAX5 		0.030 AlteredExpression disease BEFREE PAX5 gene expression is a frequent finding in superficial transitional cell carcinoma of the bladder. 16566978 2006
Entrez Id: 5245
Gene Symbol: PHB
PHB 		0.010 Biomarker disease BEFREE Prohibitin in the pathogenesis of transitional cell bladder cancer. 17465217 2007
Entrez Id: 2146
Gene Symbol: EZH2
EZH2 		0.040 PosttranslationalModification disease BEFREE EZH2 polycomb transcriptional repressor expression correlates with methylation of the APAF-1 gene in superficial transitional cell carcinoma of the bladder. 17541304 2007
Entrez Id: 4193
Gene Symbol: MDM2
MDM2 		0.010 GeneticVariation disease BEFREE MDM2 SNP309 and p53 Arg72Pro polymorphisms might influence the clinical outcome of TCCB in a distinctive way between superficial TCCB and invasive TCCB. 18575717 2008
Entrez Id: 220296
Gene Symbol: HEPACAM
HEPACAM 		0.040 AlteredExpression disease BEFREE HepaCAM expression was down-regulated in 82% (28/34) of TCCB specimens and undetectable in the 2 TCCB cell lines tested. 20205955 2010
Entrez Id: 3611
Gene Symbol: ILK
ILK 		0.020 Biomarker disease BEFREE ILK gene transcription and protein expression may be involved in the development of BTCC, so that ILK might be the new marker for early diagnosis and the new target for gene treatment. 22938462 2012
Entrez Id: 55000
Gene Symbol: TUG1
TUG1 		0.020 AlteredExpression disease BEFREE TUG1 was up-regulated in bladder urothelial carcinoma compared to paired normal urothelium. 22961206 2013
Entrez Id: 4837
Gene Symbol: NNMT
NNMT 		0.010 AlteredExpression disease BEFREE NNMT mRNA and protein levels were also determined in urine specimens obtained from patients with bladder UC and healthy subjects. 23097023 2013
Entrez Id: 378938
Gene Symbol: MALAT1
MALAT1 		0.020 AlteredExpression disease BEFREE MALAT1 was upregulated in bladder urothelial carcinoma compared with matched normal urothelium (P=.008). 23153939 2013
Entrez Id: 219541
Gene Symbol: MED19
MED19 		0.010 Biomarker disease BEFREE Med19 promotes bone metastasis and invasiveness of bladder urothelial carcinoma via bone morphogenetic protein 2. 23276457 2013
Entrez Id: 3488
Gene Symbol: IGFBP5
IGFBP5 		0.010 AlteredExpression disease BEFREE IGFBP-5 overexpression was significantly associated with advanced pT stage (p<0.001), high histological grade (UTUC, p<0.001; UBUC, p=0.035), lymph node metastasis (UTUC, p=0.006; UBUC, p=0.004), vascular invasion (UTUC, p<0.001; UBUC, p=0.003), perineural invasion (UTUC, p=0.034; UBUC, p=0.021) and frequent mitosis (UTUC, p<0.001; UBUC, p=0.023). 23539739 2013
Entrez Id: 11065
Gene Symbol: UBE2C
UBE2C 		0.010 Biomarker disease BEFREE UBE2C positivity was observed in 51 of 82 (62%) bladder urothelial carcinoma cases treated with radical cystectomy. 23826418 2013
Entrez Id: 54984
Gene Symbol: PINX1
PINX1 		0.010 Biomarker disease BEFREE PinX1 suppresses bladder urothelial carcinoma cell proliferation via the inhibition of telomerase activity and p16/cyclin D1 pathway. 24268029 2013
Entrez Id: 9043
Gene Symbol: SPAG9
SPAG9 		0.020 Biomarker disease BEFREE Sperm associated antigen 9 plays an important role in bladder transitional cell carcinoma. 24349057 2013
Entrez Id: 27253
Gene Symbol: PCDH17
PCDH17 		0.010 PosttranslationalModification disease BEFREE Protocadherin 17 promoter methylation in tumour tissue from patients with bladder transitional cell carcinoma. 24567353 2014
Entrez Id: 6283
Gene Symbol: S100A12
S100A12 		0.010 AlteredExpression disease BEFREE S100A12 and RAGE expression in human bladder transitional cell carcinoma: a role for the ligand/RAGE axis in tumor progression? 25854354 2015