Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 GeneticVariation disease BEFREE To facilitate the development of molecular based diagnostic tools and targeted therapies for this aggressive kidney cancer, we generated a translocation RCC mouse model, in which the <i>PRCC-TFE3</i> transgene is expressed specifically in kidneys leading to the development of RCC with characteristic histology. 31043488 2019
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 GeneticVariation disease BEFREE Herein, we identify a case of MITF translocation RCC with the novel PRCC-MITF gene fusion by RNA sequencing. 29148086 2018
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 Biomarker disease BEFREE All 7 PRCC-TFE3 RCCs showed positive cathepsin K immunoreactivity. 28949976 2017
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 Biomarker disease BEFREE We corroborate prior data showing that the PRCC-TFE3 RCCs are the only known Xp11 translocation RCC molecular subtype that are consistently cathepsin K positive. 26975036 2016
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 Biomarker disease BEFREE PRCC-TFE3 renal cell carcinoma in a boy with a history of contralateral mesoblastic nephroma. 16807766 2006
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 AlteredExpression disease BEFREE The endothelin axis was expressed differently in the two main subtypes of RCC and appeared to match macroscopic features commonly observed in these tumors (i.e., high expression of PPET-1 in hypervascular ccRCC contrasted against low PPET-1 and ET(A) expression in hypovascular PRCC). 15139053 2004
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 Biomarker disease BEFREE A PRCC-TFE3 fusion gene is typically encountered in t(X;1)-positive non-familial papillary RCCs and results in abrogation of the cell cycle mitotic spindle checkpoint in a dominant-negative fashion, thus leading to RCC. 12351585 2002
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 GeneticVariation disease BEFREE The papillary renal cell carcinoma (RCC)-associated (X;1)(p11;q21) translocation fuses the genes PRCC and TFE3 and leads to cancer by an unknown molecular mechanism. 11717438 2001
Entrez Id: 5546
Gene Symbol: PRCC
PRCC
0.380 Biomarker disease CTD_human