Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6757
Gene Symbol: SSX2
SSX2
0.100 GeneticVariation disease BEFREE In conclusion, the SYT-SSX fusion type is not a significant prognostic factor unlike tumor size, followed by histological grade for patients with localized synovial sarcoma in Japan. 18202796 2008
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation disease BEFREE Molecular analysis detected a fusion gene transcript of synovial sarcoma translocation (SYT) gene from chromosome 18 and synovial sarcoma X chromosome breakpoint 1 (SSX1) gene, which is believed to pathognomonic for synovial sarcoma of joint origin. 17197895 2007
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation disease BEFREE The presence of an SYT-SSX gene fusion resulting from the t(X;18) characteristic of synovial sarcoma was demonstrated by reverse transcriptase polymerase chain reaction in three of three tumors in which adequate RNA could be obtained from paraffin blocks. 10935649 2000
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation disease BEFREE Nine tumors originally diagnosed as SS were t(X;18) (SYT-SSX)-negative. 11172303 2001
Entrez Id: 6757
Gene Symbol: SSX2
SSX2
0.100 GeneticVariation disease BEFREE Here we report a case of synovial sarcoma with a novel form of the SYT-SSX2 fusion transcript, in which 75 bases were inserted at the common fusion junction. 16682293 2006
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation disease BEFREE Novel SYT-SSX fusion transcript variants in synovial sarcoma. 19837269 2009
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation disease BEFREE The prognostic impact of SYT-SSX fusion type and histological grade in pediatric patients with synovial sarcoma treated according to the CWS (Cooperative Weichteilsarkom Studie) trials. 27621063 2017
Entrez Id: 952
Gene Symbol: CD38
CD38
0.100 GeneticVariation disease BEFREE Translocations t(X;7) and t(7;14) in a synovial sarcoma. 1648957 1991
Entrez Id: 6757
Gene Symbol: SSX2
SSX2
0.100 GeneticVariation disease BEFREE As a result of the synovial sarcoma associated t(X;18) translocation, the human SYT gene on chromosome 18 is fused to either the SSX1 or the SSX2 gene on the X chromosome. 11423977 2001
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100 GeneticVariation disease BEFREE Nine tumors originally diagnosed as SS were t(X;18) (SYT-SSX)-negative. 11172303 2001
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100 GeneticVariation disease BEFREE Fluorescence In Situ Hybridization (FISH) analysis showed a rearrangement of the synaptotagmin (SYT) gene, confirming the diagnosis of SS. 27118264 2016
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation disease BEFREE Identification of the t(X;18)(p11.2;q11.2) translocation and detection of the resulting SYT-SSX1 or SYT-SSX2 fusion transcripts are useful diagnostic markers for synovial sarcoma. 9688183 1998
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation disease BEFREE The presence of an SYT-SSX gene fusion resulting from the t(X;18) characteristic of synovial sarcoma was demonstrated by reverse transcriptase polymerase chain reaction in three of three tumors in which adequate RNA could be obtained from paraffin blocks. 10935649 2000
Entrez Id: 6857
Gene Symbol: SYT1
SYT1
0.100 GeneticVariation disease BEFREE Synovial sarcoma is an aggressive sarcoma with specific reciprocal chromosomal translocation of SS18 (also known as SYT) and SSX genes. 27362474 2018
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100 GeneticVariation disease BEFREE Here we report a case of synovial sarcoma with a novel form of the SYT-SSX2 fusion transcript, in which 75 bases were inserted at the common fusion junction. 16682293 2006
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100 GeneticVariation disease BEFREE Cloning and characterization of spliced fusion transcript variants of synovial sarcoma: SYT/SSX4, SYT/SSX4v, and SYT/SSX2v. Possible regulatory role of the fusion gene product in wild type SYT expression. 11368913 2001
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100 GeneticVariation disease BEFREE Identification of the t(X;18)(p11.2;q11.2) translocation and detection of the resulting SYT-SSX1 or SYT-SSX2 fusion transcripts are useful diagnostic markers for synovial sarcoma. 9688183 1998
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100 GeneticVariation disease BEFREE The SYT-SSX1 variant of synovial sarcoma is associated with a high rate of tumor cell proliferation and poor clinical outcome. 10397263 1999
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation disease BEFREE Detection of SYT-SSX fusion gene in peripheral blood from a patient with synovial sarcoma. 11224613 2001
Entrez Id: 952
Gene Symbol: CD38
CD38
0.100 GeneticVariation disease BEFREE Oncogenesis in synovial sarcoma is driven by the chromosomal translocation t(X,18; p11,q11), which generates an in-frame fusion of the SWI/SNF subunit SS18 to the C-terminal repression domains of SSX1 or SSX2. 25614489 2015
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100 GeneticVariation disease BEFREE Prospectively, FNAs positive for the SYT-SSX fusion transcript by RT-PCR (n = 6) and, retrospectively, cases proven on histopathology and immunohistochemistry (ICC; positivity for vimentin and epithelial membrane antigen [EMA]/cytokeratin) as SS (n = 10) were included in the study. 19267417 2009
Entrez Id: 6757
Gene Symbol: SSX2
SSX2
0.100 GeneticVariation disease BEFREE Synovial sarcoma is characterized cytogenetically by an X;18 translocation [t (X;18) (p11;q11)] that results in the fusion of the SYT gene from chromosome 18 to either of two highly homologous genes at Xp11, SSX1 or SSX2. 9990487 1998
Entrez Id: 6760
Gene Symbol: SS18
SS18
0.100 GeneticVariation disease BEFREE Although the specific chromosomal translocation and fusion gene SYT-SSX in synovial sarcoma (SS) has been identified, the molecular mechanism of its tumorigenesis is largely unknown. 16556060 2005
Entrez Id: 727837
Gene Symbol: SSX2B
SSX2B
0.100 GeneticVariation disease BEFREE Synovial sarcoma is a translocation-associated sarcoma where the underlying chromosomal event generates SS18-SSX fusion transcripts. 22439931 2012
Entrez Id: 6757
Gene Symbol: SSX2
SSX2
0.100 GeneticVariation disease BEFREE Identification of novel genes, SYT and SSX, involved in the t(X;18)(p11.2;q11.2) translocation found in human synovial sarcoma. 7951320 1994