Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE Prevention of cervical cancer in up to 80-95% of patients with screen-detected CIN is dependent on the excision/ablation of the entire transformation zone. 31304554 2019
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE Educational outreach to enhance Specific Knowledge about HPV, CIN and cervical cancer is critical. 31522376 2019
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 GeneticVariation disease BEFREE However, the MTHFR C677T polymorphism was not associated with the risk of cervical cancer or CIN. 29740106 2018
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 GeneticVariation disease BEFREE The high-risk (hr) HPV-positive rate was 88.4% for CxCa and 90.1% for CIN 2/3. 29746625 2018
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE Whereas the increase in the amplification of 3q26 is noticeable already at CIN 2 + lesions (p < 0.01), 5p15 amplification is shifted up toward CIN 3/CIS (p < 0.001) and cervical cancer. 30072014 2018
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 GeneticVariation disease BEFREE These findings highlight the key role of HPV16, 58, 52 and 18 in the development of CIN and SCC in Longnan women and a fully aware of regional differences in HPV genotype distribution are tasks for cervical cancer control and prevention. 28138337 2017
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE To assess the effect of local cervical treatment for CIN and early cervical cancer on obstetric outcomes (after 24 weeks of gestation) and to correlate these to the cone depth and comparison group used. 29095502 2017
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 GeneticVariation disease BEFREE From 85 published reports, which include 3,922 cases and 2,099 noncancerous control tissue samples, 63 differentially expressed miRNAs (DEmiRNAs) were identified in different stages of cervical cancer development (CIN 1-3 and CC). 26032913 2016
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE HIV+/AIDS women have an increased risk of developing into CIN and cervical cancer compared to the general population. 27846440 2016
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE The existence of Th22, pure Th17 and Th1 cells in CIN and Cervical Cancer along with their frequency variation in different stages of cervical cancer. 26474968 2015
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE On the basis of pathological report normal were 1358, with inflammation 2441, with low grade lesion were 399, high grade lesion were 353, CIN were 19 and cervical carcinoma were 15. 26617946 2015
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE HPV detection in a self-collected vaginal swab combined with VIA for cervical cancer screening with correlation to histologically confirmed CIN. 25009070 2014
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 GeneticVariation disease BEFREE The cases were selected as to include 63 normal cases, 94 CIN cases and 23 cervical carcinoma cases. 24804816 2014
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 GeneticVariation disease BEFREE The major concern in conservative treatment is to verify whether CIN eradication was complete, since incomplete excision is associated with an increased risk of cervical cancer. 23016778 2013
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE In two case-control studies, 30 participants did not have CIN, 18 had low-grade CIN (CIN1), 64 had CIN2,3, seven had cervical cancer and the diagnosis was undefined for 27 women. 23015309 2013
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 AlteredExpression disease BEFREE TPX2 expression was found to be significantly higher in cervical carcinoma compared to normal cervical tissues and CIN. 22307108 2012
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE AQP1 was predominantly localized in the microvascular endothelial cell in the stroma of mild cervicitis, CIN and cervical carcinoma. 22901156 2012
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE We conclude that this is the first paper to point out that integration of high-risk HPVs not only 16 and 18 but also 52 and 58 is correlated with high levels of oncogene transcripts from normal cervix, CIN to cervical cancer. 21777630 2011
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE In conclusion, there was no significant association between most SNPs in MTHFR, MTR, or MTRR and the risk of CIN and cervical cancer in Korean women. 19760026 2010
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE Abbott RealTime HR HPV was evaluated with 253 cervical specimens obtained from patients with CIN 3 and 340 specimens from patients with cervical cancer to determine clinical sensitivity of the test and the prevalence of types 16 and 18. 19651365 2009
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 AlteredExpression disease BEFREE IGFBP-5 expression is up-regulated in response to progression of CIN and down-regulated in invasive cervical carcinoma. 19476635 2009
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE From a clinical point of view, testing for a broad spectrum of high-risk human papillomavirus (hrHPV) is only useful when a positive hrHPV test result is informative about the presence of high-grade cervical intraepithelial neoplasia or cervical cancer (CIN 2 or worse).Two hrHPV tests, i.e. 20129067 2009
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE Among the HPV-negative patients, two (11.8%) had CIN 1, five (29.4%) CIN 2, nine (52.9%) CIN 3 and one patient (5.9%) had microinvasive cancer of the uterine cervix. 18468341 2008
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE HPV DNA testing is a useful indicator in the management of patients with ASC-US and plays an important role in the evaluation of risk for CIN 2,3 and cervical cancer. 17355305 2007
Entrez Id: 57026
Gene Symbol: PDXP
PDXP
0.100 Biomarker disease BEFREE To evaluate selected HPV genotyping, viral load, and viral integration status as potential predictive markers for CIN progression, we performed HPV genotyping in formalin-fixed, paraffin-embedded cervical tissue with cervical carcinoma (29 cases) and CINs (CIN 1, 27 cases; CIN 2, 28 cases; CIN 3, 33 cases). 17192787 2007