| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.390 | GeneticVariation | disease | BEFREE | Inactivating mutations of the tumor suppressor gene Liver Kinase B1 (<i>LKB1</i>) are frequently detected in non-small-cell lung cancer (NSCLC) and cervical carcinoma. | 31781355 | 2019 | ||||
|
0.390 | GeneticVariation | disease | BEFREE | The liver kinase B1 (LKB1) gene is a tumor suppressor associated with the hereditary Peutz-Jeghers syndrome and frequently mutated in non-small cell lung cancer and in cervical cancer. | 30222967 | 2018 | ||||
|
0.390 | GeneticVariation | disease | BEFREE | However, the significance of LKB1 mutations in cervical cancer initiation and progress has not been examined. | 27546620 | 2017 | ||||
|
0.390 | AlteredExpression | disease | BEFREE | Gene expression profiles of cervical cancer HeLa cells stably expressing LKB1 were analyzed by microarray. | 24792998 | 2014 | ||||
|
0.390 | Biomarker | disease | BEFREE | Heightened and sustained receptor activation was demonstrated by LKB1-deficient A549 (lung) and HeLaS3 (cervical) cancer cell lines. | 24285539 | 2014 | ||||
|
0.390 | Biomarker | disease | BEFREE | Mir-155 promotes cervical cancer cell proliferation through suppression of its target gene LKB1. | 25155037 | 2014 | ||||
|
0.390 | AlteredExpression | disease | BEFREE | LKB1 expression and the integrity of LKB1-AMPK signaling were determined with immunoblot in 6 cervical cancer cell lines. | 22735790 | 2012 | ||||
|
0.390 | GeneticVariation | disease | BEFREE | Mutations in the tumor suppressor gene LKB1 are important in hereditary Peutz-Jeghers syndrome, as well as in sporadic cancers including lung and cervical cancer. | 21926085 | 2011 | ||||
|
0.390 | GeneticVariation | disease | BEFREE | Somatic LKB1 mutations promote cervical cancer progression. | 19340305 | 2009 | ||||
|
0.390 | GeneticVariation | disease | UNIPROT |