| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | phenotype | BEFREE | Spasmolytic polypeptide-expressing metaplasia (SPEM) is a regenerative lesion in the gastric mucosa and is a potential precursor to intestinal metaplasia/gastric adenocarcinoma in a chronic inflammatory setting. | 31481545 | 2019 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | In particular, intestinal metaplasia and spasmolytic polypeptide-expressing metaplasia (SPEM) have been associated with the pathological progression to intestinal-type gastric cancer. | 29427515 | 2018 | ||||
|
0.080 | AlteredExpression | phenotype | BEFREE | The serum TFF2 level cannot predict SPEM or IM in H. pylori-infected relatives of patients with gastric cancer. | 27220894 | 2017 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | Clinical significance of spasmolytic polypeptide-expressing metaplasia and intestinal metaplasia in Epstein-Barr virus-associated and Epstein-Barr virus-negative gastric cancer. | 28300576 | 2017 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | The study determined whether the children of gastric cancer patients (GCA) had genomic single nucleotide polymorphisms (SNPs) predisposed to the gastric precancerous lesions as spasmolytic polypeptide-expressing metaplasia (SPEM) or intestinal metaplasia (IM). | 25884934 | 2015 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | The analyses provided detailed molecular evidence for simultaneous intestinal metaplasia (IM) and spasmolytic polypeptide expressing metaplasia (SPEM) in atrophic corpus tissue. | 24119614 | 2013 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | Recognized precursor lesions for gastric adenocarcinoma are intestinal metaplasia and spasmolytic polypeptide expressing metaplasia (SPEM), defined here by ectopic CDX2 and TFF2 expression, respectively. | 20709804 | 2010 | ||||
|
0.080 | Biomarker | phenotype | BEFREE | Intestinal metaplasia (IM) and spasmolytic polypeptide-expressing metaplasia (SPEM) are precursors to gastric carcinogenesis. | 20398667 | 2010 |