Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.510 GeneticVariation disease BEFREE Our data indicate, that in addition to the histological and immunohistochemical evaluation, investigation of MGMT promoter methylation and in particular BRAF V600E mutations represent reliable additional tools to sustain differentiation of gcGBM from PXA on a molecular basis. 27253461 2016
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.510 Biomarker disease ORPHANET A study of clinico-pathological parameters and O⁶-methylguanine DNA methyltransferase (MGMT) promoter methylation status in the prognostication of gliosarcoma. 22380407 2012
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.510 Biomarker disease CTD_human Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastoma with a mesenchymal-epithelial transition inhibitor. 22162573 2012
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.510 Biomarker disease ORPHANET O6-methylguanine DNA methyltransferase status determined by promoter methylation and immunohistochemistry in gliosarcoma and their clinical implications. 20556478 2011
Entrez Id: 4255
Gene Symbol: MGMT
MGMT 		0.510 Biomarker disease CTD_human MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma. 20131314 2010
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 Biomarker disease CTD_human EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling. 26455392 2015
Entrez Id: 346288
Gene Symbol: SEPTIN14
SEPTIN14 		0.500 FusionGene disease ORPHANET Systematic exploration of natural and synthetic flavonoids for the inhibition of Staphylococcus aureus biofilms. 24071942 2013
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		0.500 SomaticCausalMutation disease ORPHANET The FSHD2 gene SMCHD1 is a modifier of disease severity in families affected by FSHD1. 24075187 2013
Entrez Id: 346288
Gene Symbol: SEPTIN14
SEPTIN14 		0.500 Biomarker disease CTD_human The integrated landscape of driver genomic alterations in glioblastoma. 23917401 2013
Entrez Id: 346288
Gene Symbol: SEPTIN14
SEPTIN14 		0.500 FusionGene disease ORPHANET The FSHD2 gene SMCHD1 is a modifier of disease severity in families affected by FSHD1. 24075187 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 Biomarker disease CTD_human The integrated landscape of driver genomic alterations in glioblastoma. 23917401 2013
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		0.500 SomaticCausalMutation disease ORPHANET Genomics informs glioblastoma biology. 24071842 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 FusionGene disease ORPHANET Systematic exploration of natural and synthetic flavonoids for the inhibition of Staphylococcus aureus biofilms. 24071942 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 FusionGene disease ORPHANET The FSHD2 gene SMCHD1 is a modifier of disease severity in families affected by FSHD1. 24075187 2013
Entrez Id: 8216
Gene Symbol: LZTR1
LZTR1 		0.500 Biomarker disease CTD_human The integrated landscape of driver genomic alterations in glioblastoma. 23917401 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.500 Biomarker disease CTD_human Randomized phase II trial of erlotinib versus temozolomide or carmustine in recurrent glioblastoma: EORTC brain tumor group study 26034. 19204207 2009
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 GeneticVariation disease BEFREE Previously, single-gene study identified genetic changes in TP53, PTEN and TERT promoter mutation in gcGBM. 30861589 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 GeneticVariation disease BEFREE Fifty-nine percent of gcGB samples but only 18% of the GB samples showed p53 mutations. 20467329 2010
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 Biomarker disease ORPHANET Long-term survival with glioblastoma multiforme. 17785346 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 Biomarker disease BEFREE This article gives an outline of molecular biological approaches to analysis of neurological disorders such as giant cell glioblastoma (GGBM) and amyotrophic lateral sclerosis (ALS), and their respective animal models: p53 knockout mice for GGBM and mutant superoxide dismutase-1 transgenic mice for ALS. 12564775 2002
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.340 GeneticVariation disease BEFREE In this study, we assessed p53 mutations and EGFR expression in the giant cell glioblastoma. 9370234 1997
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		0.310 GeneticVariation disease BEFREE IDH1 R132 and IDH R172 mutations were not present in any of the PXA and gcGBM cases. 27253461 2016
Entrez Id: 3417
Gene Symbol: IDH1
IDH1 		0.310 Biomarker disease ORPHANET An integrated genomic analysis of human glioblastoma multiforme. 18772396 2008
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.310 Biomarker disease CTD_human Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) cells by isoflavones. 16598420 2006
Entrez Id: 1950
Gene Symbol: EGF
EGF 		0.310 AlteredExpression disease BEFREE p53 mutations versus EGF receptor expression in giant cell glioblastomas. 9370234 1997