Gene: MAP2K7 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		0.030 Biomarker disease BEFREE We identified recurrent mutations involving the RAS-MAPK signaling pathway (MAP2K1, KRAS, NRAS, BRAF, PTPN11, NF1, CBL) in a majority (57%) of histiocytic sarcoma cases and report a clinical response to a MEK inhibitor (Cobimetinib) in a patient with a NF1-mutated histiocytic sarcoma. 30626916 2019
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		0.030 Biomarker disease BEFREE MEK inhibition may represent a useful treatment option in histiocytic sarcoma. 30361829 2019
Entrez Id: 5609
Gene Symbol: MAP2K7
MAP2K7 		0.030 Biomarker disease BEFREE Targeting MEK in a Translational Model of Histiocytic Sarcoma. 30135215 2018