Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
0.510 Biomarker disease BEFREE In conclusion, our association results suggest that TSHR gene is not a susceptibility gene for FIDD in the iodine-deficient areas of China. 15911145 2005
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
0.510 Biomarker disease CTD_human The W546X mutation of the thyrotropin receptor gene: potential major contributor to thyroid dysfunction in a Caucasian population. 12629076 2003
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
0.510 Biomarker disease MGD
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.500 Biomarker disease CTD_human Clinical and genetic characteristics of congenital hypothyroidism due to mutations in the thyroid peroxidase (TPO) gene in Israelis. 17381485 2007
Entrez Id: 50506
Gene Symbol: DUOX2
DUOX2
0.500 Biomarker disease CTD_human Three mutations (p.Q36H, p.G418fsX482, and g.IVS19-2A>C) in the dual oxidase 2 gene responsible for congenital goiter and iodide organification defect. 16322276 2006
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.500 Biomarker disease CTD_human Total iodide organification defect: clinical and molecular characterization of an Italian family. 16187919 2005
Entrez Id: 50506
Gene Symbol: DUOX2
DUOX2
0.500 Biomarker disease CTD_human Persistent mild hypothyroidism associated with novel sequence variants of the DUOX2 gene in two siblings. 16134168 2005
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.500 Biomarker disease CTD_human Congenital hypothyroidism with goiter in toy fox terriers. 12564727 2003
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.500 Biomarker disease CTD_human Thyroperoxidase gene mutations in congenital goitrous hypothyroidism with total and partial iodide organification defect. 14751036 2003
Entrez Id: 50506
Gene Symbol: DUOX2
DUOX2
0.500 Biomarker disease MGD
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.500 Biomarker disease MGD
Entrez Id: 3547
Gene Symbol: IGSF1
IGSF1
0.300 Biomarker disease CTD_human Loss-of-function mutations in IGSF1 cause an X-linked syndrome of central hypothyroidism and testicular enlargement. 23143598 2012
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
0.200 Therapeutic disease RGD Iodine plus n-3 fatty acid supplementation augments rescue of postnatal neuronal abnormalities in iodine-deficient rat cerebellum. 23312094 2013
Entrez Id: 10092
Gene Symbol: ARPC5
ARPC5
0.200 Biomarker disease RGD Effects of hypothyroidism on expression of CRMP2B and ARPC5 during development of the rat frontal cortex. 23459330 2013
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
0.200 Biomarker disease RGD Developmentally-induced hypothyroidism alters the expression of Egr-1 and Arc genes and the sensitivity to cannabinoid agonists in the hippocampus. Possible implications for memory and learning. 23079472 2013
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
0.200 Biomarker disease RGD Congenital hypothyroidism alters the oxidative status, enzyme activities and morphological parameters in the hippocampus of developing rats. 23693027 2013
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.200 Therapeutic disease RGD Changes in growth hormone (GH), GH receptor, and GH signal transduction in hippocampus of congenital hypothyroid rats. 21162131 2011
Entrez Id: 2690
Gene Symbol: GHR
GHR
0.200 Therapeutic disease RGD Changes in growth hormone (GH), GH receptor, and GH signal transduction in hippocampus of congenital hypothyroid rats. 21162131 2011
Entrez Id: 10476
Gene Symbol: ATP5PD
ATP5PD
0.200 Biomarker disease RGD [Proteomic changes in cerebral cortex of neonatal rats with experimental congenital hypothyroidism]. 21575372 2011
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
0.200 Biomarker disease RGD Evidence of a bigenomic regulation of mitochondrial gene expression by thyroid hormone during rat brain development. 20515651 2010
Entrez Id: 4741
Gene Symbol: NEFM
NEFM
0.200 Biomarker disease RGD Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. 18845185 2008
Entrez Id: 4744
Gene Symbol: NEFH
NEFH
0.200 Biomarker disease RGD Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. 18845185 2008
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
0.200 Biomarker disease RGD Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. 18845185 2008
Entrez Id: 3625
Gene Symbol: INHBB
INHBB
0.200 Biomarker disease RGD Developmental expression of testis messenger ribonucleic acids in the rat following propylthiouracil-induced neonatal hypothyroidism. 7819453 1994
Entrez Id: 632
Gene Symbol: BGLAP
BGLAP
0.200 Biomarker disease RGD Studies on gene expression in calvaria and serum levels of insulin-like growth factor-I and bone Gla protein in the methimazole-induced congenital hypothyroid rat. 7920889 1993