Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | group | BEFREE | In fact, serum albumin may undergo structural changes by glycation which impacts on its function and plays a major role in the genesis of diabetes mellitus complications. | 31734145 | 2020 | ||||
|
0.070 | Biomarker | group | BEFREE | Diabetic kidney disease (DKD), defined as reduced glomerular filtration rate (GFR), elevated urine albumin excretion, or both that is clinically attributable to diabetes, is a common and morbid diabetes complication. | 30282055 | 2018 | ||||
|
0.070 | AlteredExpression | group | BEFREE | Checking and maintaining low glycated albumin levels would prevent the formation of AGE and may be useful to prevent the onset or progression of diabetes complications. | 28504612 | 2018 | ||||
|
0.070 | Biomarker | group | BEFREE | Ischemia Modified Albumin Test to Detect Early Diabetic Complications. | 29173357 | 2017 | ||||
|
0.070 | GeneticVariation | group | BEFREE | A locus on chromosome 1, rs7533564 (P = 1.9 × 10(-9)), was associated with skin intrinsic fluorescence measured by SCOUT DS (excitation 375 nm, emission 435-655 nm), which remained significant after adjustment for time-weighted HbA1c (P = 1.7 × 10(-8)). rs7533564 was associated with mean HbA1c in meta-analysis (P = 0.0225), mean glycated albumin (P = 0.0029), and glyoxal hydroimidazolones (P = 0.049), an AGE measured in skin biopsy collagen, in DCCT. rs7533564 was not associated with diabetes complications in DCCT/EDIC or with SF in subjects without diabetes (nondiabetic [ND]) (N = 8,721). | 27207532 | 2016 | ||||
|
0.070 | AlteredExpression | group | BEFREE | There was no correlation between the level of TNF receptor II and the levels of transaminases, albumin, and creatinine in the different groups or the degree of microalbuminuria in the groups of patients with diabetic complications. | 22068019 | 2011 | ||||
|
0.070 | Biomarker | group | LHGDN | Thermodynamic analysis of human serum albumin interactions with glucose: insights into the diabetic range of glucose concentration. | 12009306 | 2002 |