Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3630
Gene Symbol: INS
INS
0.500 Biomarker disease CTD_mouse Inhibition of SREBP With Fatostatin Does Not Attenuate Early Diabetic Nephropathy in Male Mice. 29420703 2018
Entrez Id: 3630
Gene Symbol: INS
INS
0.500 Therapeutic disease CTD_human Cortical and hippocampal mitochondria bioenergetics and oxidative status during hyperglycemia and/or insulin-induced hypoglycemia. 20620209 2010
Entrez Id: 3630
Gene Symbol: INS
INS
0.500 Biomarker disease CTD_mouse A sensitized screen of N-ethyl-N-nitrosourea-mutagenized mice identifies dominant mutants predisposed to diabetic nephropathy. 17151334 2007
Entrez Id: 10019
Gene Symbol: SH2B3
SH2B3
0.300 Biomarker disease CTD_human Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. 30224649 2018
Entrez Id: 7297
Gene Symbol: TYK2
TYK2
0.300 Biomarker disease CTD_human Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. 30224649 2018
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA
0.300 Biomarker disease CTD_human Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. 30224649 2018
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
0.300 Biomarker disease CTD_human Fine-mapping and functional studies highlight potential causal variants for rheumatoid arthritis and type 1 diabetes. 30224649 2018
Entrez Id: 3119
Gene Symbol: HLA-DQB1
HLA-DQB1
0.300 Biomarker disease CTD_human Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk. 26168013 2015
Entrez Id: 3123
Gene Symbol: HLA-DRB1
HLA-DRB1
0.300 Biomarker disease CTD_human Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk. 26168013 2015
Entrez Id: 3117
Gene Symbol: HLA-DQA1
HLA-DQA1
0.300 Biomarker disease CTD_human Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk. 26168013 2015
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.300 Biomarker disease CTD_human Activating germline mutations in STAT3 cause early-onset multi-organ autoimmune disease. 25038750 2014
Entrez Id: 3479
Gene Symbol: IGF1
IGF1
0.300 Therapeutic disease CTD_human Reducing blood glucose levels in TIDM mice with an orally administered extract of sericin from hIGF-I-transgenic silkworm cocoons. 24632065 2014
Entrez Id: 26291
Gene Symbol: FGF21
FGF21
0.300 Therapeutic disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 9131
Gene Symbol: AIFM1
AIFM1
0.300 Biomarker disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.300 Biomarker disease CTD_human Mechanism of BDE209-induced impaired glucose homeostasis based on gene microarray analysis of adult rat liver. 23640034 2013
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3
0.300 Biomarker disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 100506742
Gene Symbol: CASP12
CASP12
0.300 Biomarker disease CTD_human Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial- and endoplasmic reticulum stress-dependent pathways in the mouse model. 23499715 2013
Entrez Id: 3458
Gene Symbol: IFNG
IFNG
0.300 Biomarker disease CTD_human Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. 21340626 2011
Entrez Id: 6364
Gene Symbol: CCL20
CCL20
0.300 Therapeutic disease CTD_human Prevention and treatment of diabetes with resveratrol in a non-obese mouse model of type 1 diabetes. 21340626 2011
Entrez Id: 4842
Gene Symbol: NOS1
NOS1
0.300 Biomarker disease CTD_human Chronic resveratrol treatment restores vascular responsiveness of cerebral arterioles in type 1 diabetic rats. 21666113 2011
Entrez Id: 4846
Gene Symbol: NOS3
NOS3
0.300 Biomarker disease CTD_human Chronic resveratrol treatment restores vascular responsiveness of cerebral arterioles in type 1 diabetic rats. 21666113 2011
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22
0.300 Biomarker disease CTD_human Inhibition of lymphoid tyrosine phosphatase by benzofuran salicylic acids. 21190368 2011
Entrez Id: 1356
Gene Symbol: CP
CP
0.300 Biomarker disease CTD_human Antioxidant potential, paraoxonase 1, ceruloplasmin activity and C-reactive protein concentration in diabetic retinopathy. 20012460 2010
Entrez Id: 1401
Gene Symbol: CRP
CRP
0.300 Biomarker disease CTD_human Antioxidant potential, paraoxonase 1, ceruloplasmin activity and C-reactive protein concentration in diabetic retinopathy. 20012460 2010
Entrez Id: 55315
Gene Symbol: SLC29A3
SLC29A3
0.300 Biomarker disease CTD_human Mutations in SLC29A3, encoding an equilibrative nucleoside transporter ENT3, cause a familial histiocytosis syndrome (Faisalabad histiocytosis) and familial Rosai-Dorfman disease. 20140240 2010