Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3845
Gene Symbol: KRAS
KRAS
0.060 GeneticVariation disease BEFREE "Low-risk" and "high-risk" HPV-infection and K-ras gene point mutations in human cervical cancer: a study of 31 cases. 11569923 2001
Entrez Id: 4153
Gene Symbol: MBL2
MBL2
0.070 Biomarker disease BEFREE <b>Aim:</b> To identify the role of mannose binding lectin (MBL) in susceptibility to HPV infection and to explore the relationship between MBL and response to intralesional Candida antigen immunotherapy of wart. 31469597 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.100 AlteredExpression disease BEFREE <b>CONCLUSIONS:</b> These results suggest that hr-HPV types are not associated with the development of ESCC and that p53 and p16 protein expression have no relationship with HPV infection in normal or cancerous esophagus. 28529620 2017
Entrez Id: 115482713
Gene Symbol: H3P10
H3P10
0.100 AlteredExpression disease BEFREE <b>CONCLUSIONS:</b> These results suggest that hr-HPV types are not associated with the development of ESCC and that p53 and p16 protein expression have no relationship with HPV infection in normal or cancerous esophagus. 28529620 2017
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.100 AlteredExpression disease BEFREE <b>CONCLUSIONS:</b> These results suggest that hr-HPV types are not associated with the development of ESCC and that p53 and p16 protein expression have no relationship with HPV infection in normal or cancerous esophagus. 28529620 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 AlteredExpression disease BEFREE <b>Results:</b> The association of HPV infection and EGFR expression was found to be statistically significant, and so was the difference in survival between patient groups with different HPV to EGFR expression ratio. 31430224 2019
Entrez Id: 968
Gene Symbol: CD68
CD68
0.020 GeneticVariation disease BEFREE <i>Results.</i> High counts of CD68+ and CD163+ macrophages were associated with hr-HPV infection (both <i>p</i> < 0.05) and positively correlated with cervical carcinogenesis (Spearman's rho = 0.478, <i>p</i> = 0.000; Spearman's rho = 0.676, <i>p</i> =0.000, respectively). 29151975 2017
Entrez Id: 9332
Gene Symbol: CD163
CD163
0.020 GeneticVariation disease BEFREE <i>Results.</i> High counts of CD68+ and CD163+ macrophages were associated with hr-HPV infection (both <i>p</i> < 0.05) and positively correlated with cervical carcinogenesis (Spearman's rho = 0.478, <i>p</i> = 0.000; Spearman's rho = 0.676, <i>p</i> =0.000, respectively). 29151975 2017
Entrez Id: 182
Gene Symbol: JAG1
JAG1
0.010 AlteredExpression disease BEFREE 40 non-neoplastic cervical tissues, 30 precancer and 118 tumor specimens (total 188 tissue biopsies) were studied for the expression of the JAG1 protein through immunohistochemistry, immunoblotting and for HPV infection. 29921897 2018
Entrez Id: 2263
Gene Symbol: FGFR2
FGFR2
0.020 Biomarker disease BEFREE 5'-Bromo-deoxyuridine incorporation assay demonstrated that expression of 16E5 induces a decrease in the growth response to the receptor ligands as a consequence of KGFR down-modulation, suggesting that 16E5 might have a role on HPV infection in perturbing the KGFR-mediated physiological behavior of confluent keratinocytes committed to differentiation. 21625213 2011
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.100 Biomarker disease BEFREE 94.7% of the cervical cancer and 84.4% of the high grade lesions with a strong and full thickness staining for p16(INK4a) were positive for HPV infection; p16(INK4a) immunoexpression increased with worsening grade of cervical intraepithelial neoplasia. 22585722 2012
Entrez Id: 11186
Gene Symbol: RASSF1
RASSF1
0.080 AlteredExpression disease BEFREE HPV infection does not correlate with RASSF1A methylation status in AC of the uterine cervix, but the absence of RASSF1A methylation in SCC of the uterine cervix coupled with the high incidence of HPV 16 infection in this subtype is in accord with previous reports. 12912945 2003
Entrez Id: 5068
Gene Symbol: REG3A
REG3A
0.050 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 11333
Gene Symbol: PDAP1
PDAP1
0.050 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 11334
Gene Symbol: TUSC2
TUSC2
0.040 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 55149
Gene Symbol: MTPAP
MTPAP
0.040 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 50807
Gene Symbol: ASAP1
ASAP1
0.040 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 55
Gene Symbol: ACP3
ACP3
0.040 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 10914
Gene Symbol: PAPOLA
PAPOLA
0.040 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 8853
Gene Symbol: ASAP2
ASAP2
0.040 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 10884
Gene Symbol: MRPS30
MRPS30
0.040 Biomarker disease BEFREE Human papillomavirus infection test results detected by Southern blot hybridization and polymerase chain reaction from physician-administered and MY-PAP self-administered cervicovaginal lavage were paired for comparison. 1332474 1992
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2
0.030 Biomarker disease BEFREE Human papillomavirus infection in Egyptian esophageal carcinoma: correlation with p53, p21, mdm2, C-erbB2 and impact on survival. 15693850 2005
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A
0.100 AlteredExpression disease BEFREE Human papillomavirus infection and p16(INK4a) protein expression in vulvar intraepithelial neoplasia and invasive squamous cell carcinoma. 15870532 2005
Entrez Id: 7057
Gene Symbol: THBS1
THBS1
0.010 Biomarker disease BEFREE HPV infection was detected in 11 of 24 cases (46%), and TSP-1, RASSF1-A and p16 genes were hypermethylated in 46%, 42% and 38% of the tumours, respectively. 18336597 2008
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2
0.030 AlteredExpression disease BEFREE HPV infection was associated in a borderline manner to the expression of COX-2 (P = 0.04; OR = 2.3 95% CI = 1.0-5.4). 18773440 2008