Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | Subgroup analysis revealed that the GSTM1 null variant caused cervical lesions among HPV infection cases (OR = 1.69, P = .02) and among the Chinese and Indian populations (OR = 2.24 and OR = 1.87, respectively, P < .001). | 31593112 | 2019 | ||||
|
0.080 | Biomarker | disease | BEFREE | Glutathione S-transferase M1 and T1 Polymorphisms, Cigarette Smoking and HPV Infection in Precancerous and Cancerous Lesions of the Uterine Cervix. | 26434855 | 2015 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Functional variants in CYP1A1 and GSTM1 are associated with clearance of cervical HPV infection. | 25281494 | 2014 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Smoking and HPV infection modified the association between the null GSTM1 genotype and CC. | 24391774 | 2013 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Significant difference was observed between GSTM1 - GSTT1 null genotypes (P = 0.04, P = 0.001 respectively) and HPV infection (P<0.001) with mtDNA content variation in cases and controls. | 23469236 | 2013 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Although the GSTM1 and GSTT1 genotype was not significantly associated with cervical cancer development for all women, the GSTM1 null genotype was significantly associated with an increased risk of cervical cancer development in women with high-risk HPV infection (OR = 2.9, 95% CI: 1.0-8.2). | 15047208 | 2004 | ||||
|
0.080 | Biomarker | disease | BEFREE | The GSTM1 null genotype was associated with a significant 3.3-fold increased risk for neoplasia (95% CI = 1.0-11.8) compared to women who were GSTM1-positive after adjustment for smoking and HPV infection. | 12552594 | 2003 | ||||
|
0.080 | Biomarker | disease | BEFREE | The GSTM1 null genotype was associated with a significant 3.4 fold increase in risk (95% CI=1.0-11.8) compared with those who were GSTM1 positive, after adjustment for smoking and HPV infection. | 14644338 | 2003 |