|
HLA-DRB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results confirmed the assessment of DRB1*13 as a protective marker in HPV infection outcome. our study also revealed protective association of homozygous haplotype DRB1*15- DQB1*06 with cervical cancer.
|
25673541 |
2014 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
HPV infection and human leukocyte antigen (HLA) class II alleles in HLA-DRB1, 3-7, and 9 were detected.
|
25223804 |
2014 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
This study examined the associations between the development of Kazakh ESCC and the determinant factors including HLA-DRB1*0901, 1501; DQB1*0301, 0602; high-risk HPV infection in the area of Xinjiang, China.
|
22588649 |
2012 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The DRB1*13 allele/DRB1*13-DQB1*06 haplotype was strongly protective against risk to HPV infection (p(c) < 0.002) as well as cervical cancer (p(c) 0.01).
|
19272325 |
2009 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association between HLA-DRB1 polymorphism, high-risk HPV infection and cervical neoplasia in southern Chinese.
|
17516530 |
2007 |
|
HLA-DRB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
HLA DRB1*13 was associated with cumulative risk of HPV infections (odds ratio [OR], 1.7 [95% confidence interval {CI}, 1.0-2.8]), for oncogenic HPV (OR, 1.6 [95% CI, 0.9-2.8]), and for HPV-16 (OR, 2.0 [95% CI, 0.9-4.4]).
|
17538887 |
2007 |
|
HLA-DRB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Association of HLA-DR4 (DRB1*0404) with human papillomavirus infection in patients with focal epithelial hyperplasia.
|
15492185 |
2004 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The HLA class II alleles DRB1*1501 and DQB1*0602 have previously been associated with an increased risk of HPV infection, and carriers of these alleles also tend to have more long-term infections.
|
12237892 |
2002 |
|
HLA-DRB1
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
There was no statistically significant association between HLA-DRB1 expression and TSCC or HPV infection.
|
11948119 |
2002 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The DRB1*0301-DQB1*0201 haplotype was associated with a 2-fold reduction in risk for transient and persistent HPV infections.
|
12134251 |
2002 |
|
HLA-DRB1
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In previous studies, the HLA class II haplotype HLA DRB1*0401-DQB1*0301 was shown to correlate with susceptibility to HPV infection, CIN and cervical cancer while DRB1*0101-DQB1*0501 indicated protection.
|
11562779 |
2001 |
|
HLA-DRB1
|
0.100 |
Biomarker
|
disease |
BEFREE |
Carriers of DQB1*0602 and DRB1*1501 were more frequent in the group with long-term HPV infections, indicating that these class II alleles contribute to the inability to clear an HPV infection.
|
11519043 |
2001 |