Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
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0.070 | GeneticVariation | disease | BEFREE | The data obtained suggest that HIV-infected women are more susceptible to be infected by low-risk HPV (LR-HPV) genotypes than by high-risk (HR-HPV), and Pro72Pro of TP53 gene and TG of MDM2 SNP309 genotypes apparently seem to be protective factors among HIV-infected women for HPV acquisition and HR-HPV infection, respectively, in a sample of Southern Brazilian woman. | 25181402 | 2015 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | To investigate the associations of TP53 R72P and MDM2 T309G SNPs with HPV infection status, HPV oncogenic risk and HIV infection status. | 24586820 | 2014 | ||||
|
0.070 | Biomarker | disease | BEFREE | In conclusion, Arginine at codon72 of p53 and GG genotype at 309 in P2 of MDM2 together reveal a direct proportionality with the tumor grade of cervical cancer along with HPV infection in postmenopausal women. | 23210739 | 2013 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Since the role of human papillomavirus (HPV) infection in oral carcinogenesis is still unclear, the purpose of this study was to verify the association between the expression of p27, mdm2 and cathepsin B and by HPV-related oral lesions. | 19811804 | 2011 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | MDM2-SNP309 (T/G) and high-risk HPV infection may be closely associated with cervical carcinogenesis in a Japanese population. | 20538323 | 2010 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Mdm2 expression was assessed by immunohistochemistry and HPV infection was assessed by polymerase chain reaction of tumour DNA for HPV 16, 18 and 33. | 10646894 | 2000 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Since p53 mutations, MDM2 overexpression, and HPV infection are all considered to abrogate the normal function of p53 protein, each of these genetic changes may be equally important in tumorigenesis. | 9816044 | 1995 |