| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | AlteredExpression | disease | BEFREE | We investigated the role of AQP1 in VM, and its interaction with the pro-angiogenic factor vascular endothelial growth factor A (VEGFA), which is variably expressed in MM. | 29104239 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | Our results indicate that VEGF-CRAd exerts an oncolytic effect on MM cells and that intrapleural instillation of VEGF-CRAd is safe and might represent a promising therapeutic strategy for MPM. | 27783867 | 2017 | ||||
|
0.080 | Biomarker | disease | BEFREE | Our data suggest that the downregulated expression of SEMA3A and several SEMA3s results in a loss of inhibitory activities in tumor angiogenesis and tumor growth of VEGFA; therefore, it may play an important role on the pathogenesis of the epithelioid type of MM. | 21842119 | 2011 | ||||
|
0.080 | Biomarker | disease | BEFREE | Administration of recombinant PlGF-2 did not elicit a significant stimulation of MM cell growth, while it was associated with a transient phosphorylation of Akt, suggesting that PlGF-2 could activate downstream effectors of proliferative and cytoprotective signals via VEGF-R1 in MM cells. | 19505392 | 2009 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | Although VEGF expression might be important for tumor development and maintenance, it was not identified as a prognostic factor in malignant mesothelioma. | 17214348 | 2007 | ||||
|
0.080 | Biomarker | disease | BEFREE | Vascular endothelial growth factor (VEGF) is an autocrine growth factor for MM. | 12594815 | 2003 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | High levels of VEGF were detected in conditioned media of each of two MM cells that tested positive for SV40 by PCR amplification and Southern blot hybridization and for Tag transcript by reverse transcription- polymerase chain reaction (RT-PCR) and immunoprecipitation. | 11804869 | 2002 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | To investigate endothelial nitric oxide synthase (eNOS) expression in malignant mesothelioma and its association with expression of vascular endothelial growth factor (VEGF), its receptors FLK1 and FLT1, and vascular density. | 11493335 | 2001 |