| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | EGFR and PTEN expressions were positive in 22 (66.67%) and 7 (21.21%) epithelioid MPeM patients, respectively. | 30863440 | 2019 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | First-generation tyrosine kinase inhibitors against epidermal growth factor receptor (EGFR) did not show any significant activity in MPM. | 30450291 | 2018 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | EGFR mutations were previously found in patients suffering from peritoneal mesothelioma but have not yet been described in pleural mesothelioma. | 25679064 | 2015 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Sequence analysis of the EGFR TK domain revealed the presence of a silent polymorphism (c.2607G → A, Q787Q) at exon 20 of both peritoneal mesothelioma cell lines as well as tumor specimens. | 22426987 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Five EGFR missense mutations were detected in six of the 38 patients (16%); two of these mutations were novel, two were originally detected in non-small cell lung carcinoma, and one resembled a location previously noted for malignant peritoneal mesothelioma. | 22412050 | 2012 | ||||
|
0.080 | AlteredExpression | disease | BEFREE | An evaluation of epidermal growth factor receptor (EGFR) phenotypic expression in malignant pleural and peritoneal mesothelioma was undertaken, using immunohistochemical (IHC) and fluorescence in situ hybridization (FISH) analysis. | 22449226 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma. | 20942962 | 2010 | ||||
|
0.080 | Biomarker | disease | BEFREE | Novel and existing mutations in the tyrosine kinase domain of the epidermal growth factor receptor are predictors of optimal resectability in malignant peritoneal mesothelioma. | 18998063 | 2009 |